| Name | demethylase |
|---|---|
| Synonyms | DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases… |
| Name | α-chlorohydrin |
|---|---|
| CAS | 3-chloro-1,2-propanediol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6864844 | Fruncillo RJ, DiGregorio GJ: The effect of thermal injury on drug metabolism in the rat. J Trauma. 1983 Jun;23(6):523-9. The activity of p-nitroanisole O-demethylase was significantly depressed in male rats at 5, 10, and 17 days post-16% burn. |
1(0,0,0,1) | Details |
| 926208 | Feuer G, Balazs T, Farkus R, Ilyas MS: Effect of 2-chloroethanol on hepatic microsomal enzymes in the rat. J Toxicol Environ Health. 1977 Oct;3(3):569-76. A significant reduction in activities of drug-metabolizing enzymes (aminopyrine N-demethylase, 3-hydroxylase) and a marked decrease of glucose 6-phosphatase were seen in both sexes given dose levels of 20 mg/kg sc daily for 7 days. |
1(0,0,0,1) | Details |
| 11201665 | De Smet K, Bruning T, Blaszkewicz M, Bolt HM, Vercruysse A, Rogiers V: Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes. Arch Toxicol. 2000 Dec;74(10):587-92. Endpoints studied were albumin secretion and the cytochrome P450 (CYP)-dependent enzymatic activities ethoxyresorufin O-deethylase (EROD), pentoxyresorufin O-depentylase (PROD) and N-nitrosodimethylamine demethylase (NDMA). |
1(0,0,0,1) | Details |