Protein Information

Name P glycoprotein
Synonyms ABC20; MDR1; ABCB 1; ABCB1; ATP binding cassette sub family B member 1; CD243; CD243 antigen; CLCS…

Compound Information

Name sodium cyanide
CAS sodium cyanide (Na(CN))

Reference List

PubMed Abstract RScore(About this table)
11737157 Potschka H, Loscher W: In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats. Epilepsia. 2001 Oct;42(10):1231-40.

METHODS: Three different P-gp inhibitors, sodium cyanide, verapamil, and PSC 833, were used.
37(0,1,1,7) Details
9864272 Burgio DE, Gosland MP, McNamara aPJ: Effects of P-glycoprotein modulators on etoposide elimination and central nervous system distribution. J Pharmacol Exp Ther. 1998 Dec;287(3):911-7.

Rats received sodium cyanide (1 or 100 mM), trifluoperazine (30 mM) or cyclosporine (4.14 mM) via microdialysis probe at 3.5 hr after etoposide infusion initiation.
3(0,0,0,3) Details