| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | azinphos-methyl |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1595894 | Kumaran S, Tran-Minh C: Determination of organophosphorous and insecticides by flow injection analysis. Anal Biochem. 1992 Jan;200(1):187-94. A flow injection system, incorporating an acetylcholinesterase (AChE) single bead string reactor (SBSR), for the determination of some organophosphorous (azinphos-ethyl, azinphos-methyl, bromophos-methyl, dichlorovos, fenitrothion, malathion, paraoxon, parathion-ethyl and parathion-methyl) and insecticides (carbofuran and carbaryl) is presented. |
6(0,0,1,1) | Details |
| 11695191 | Clark JM, Lee SH, Kim HJ, Yoon KS, Zhang A: DNA-based genotyping techniques for the detection of point mutations associated with insecticide resistance in Colorado potato beetle Leptinotarsa decemlineata. Pest Manag Sci. 2001 Oct;57(10):968-74. Three DNA-based genotyping techniques, bi-directional PCR amplification of specific allele (bi-PASA), single-stranded conformational polymorphism (SSCP) and minisequencing, have been developed and compared for the detection of the S291G (insensitive acetylcholinesterase) and L1014F (insensitive sodium channel) mutations associated with azinphos-methyl and permethrin resistance, respectively, in the Colorado potato beetle (Leptinotarsa decemlineata). |
6(0,0,1,1) | Details |
| 16876707 | Cassanelli S, Reyes M, Rault M, Carlo Manicardi G, Sauphanor B: Acetylcholinesterase mutation in an insecticide-resistant population of the codling moth Cydia pomonella (L.). Insect Biochem Mol Biol. 2006 Aug;36(8):642-53. Epub 2006 May 25. Two strains of Cydia pomonella (L.) (Lepidoptera: Tortricidae) were selected in the lab by exposure to increasing concentrations of diflubenzuron (Rdfb strain) or azinphos-methyl (Raz strain). |
4(0,0,0,4) | Details |
| 8212025 | Keeble VB, Correll L, Ehrich M: Evaluation of knit glove fabrics as barriers to dermal absorption of organophosphorus insecticides using an in vitro test system. Toxicology. 1993 Aug 27;81(3):195-203. Cotton and synthetic knit glove fabrics in combination with an in vitro skin model were used to examine the capability of fabric to decrease the dermal absorption of the organophosphorus insecticides azinphos-methyl, paraoxon, and malathion. Capability for inhibition of acetylcholinesterase was determined in samples of media taken from under the skin barrier after the skin model, with or without fabric protection, had been exposed to the test compounds for 4 h. |
3(0,0,0,3) | Details |
| 10632139 | Akgur SA, Ozturk P, Sozmen EY, Delen Y, Tanyalcin T, Ege B: Paraoxonase and acetylcholinesterase activities in humans exposed to organophosphorous compounds. J Toxicol Environ Health A. 1999 Dec 24;58(8):469-74. Both serum cholinesterase and PON1 activities were measured spectrophotometrically from 18 male agricultural workers who were chronically exposed to azinphos methyl, chlorpyriphos, or malathion and other pesticides during cereal spraying, transportation, and storage. |
3(0,0,0,3) | Details |
| 7097799 | Skinner CS, Kilgore WW: Acute dermal toxicities of various organophosphate insecticides in mice. J Toxicol Environ Health. 1982 Mar;9(3):491-7. Values were simultaneously generated for the ED50 (milligrams per kilogram) for both cholinesterase and acetylcholinesterase. Cholinesterase ED50 values roughly agreed with LD50 values for mevinphos, parathion, methyl parathion, and azinphos-methyl, but diazinon appeared much more inhibitory of blood than neuronal cholinesterase. |
1(0,0,0,1) | Details |
| 19674799 | Tryfonos M, Papaefthimiou C, Antonopoulou E, Theophilidis G: Comparing the inhibitory effects of five protoxicant organophosphates (azinphos-methyl, parathion-methyl, chlorpyriphos-methyl, methamidophos and diazinon) on the spontaneously beating auricle of Sparus aurata: an in vitro study. Aquat Toxicol. 2009 Sep 14;94(3):211-8. Epub 2009 Jul 16. Organophosphates (OPs) can provoke toxicity by inhibiting acetylcholinesterase (AChE) in non-target organisms, like fish. |
1(0,0,0,1) | Details |
| 224645 | Sterri SH, Rognerud B, Fiskum SE, Lyngaas S: Effect of toxogonin and P2S on the toxicity of carbamates and organophosphorus compounds. Acta Pharmacol Toxicol. 1979 Jul;45(1):9-15. Toxogonin (80 mg/kg intraperitoneally) given 15 min. prior to the administration of organophosphorus insecticides dimethoate, malathion, parathion and azinphos-methyl, organophosphorus warfare agents soman and tabun, or carbamates physostigmine, pyridostigmine and aldicarb, reduced the toxicity in mice of these agents by increasing their LD50 dose 1.5-3 fold. The acetylcholinesterase activity in erythrocytes, cerebrum and diaphragm of surviving mice 20 hours after organophosphate intoxication was similar both in toxogonin and P2S treated animals and untreated animals. |
1(0,0,0,1) | Details |
| 11005678 | Bailey BJ, Jenkins JJ: Association of azinphos-methyl with rat erythrocytes and hemoglobin. . Arch Toxicol. 2000 Aug;74(6):322-8. |
0(0,0,0,0) | Details |
| 8658539 | Marinovich M, Ghilardi F, Galli CL: Effect of pesticide mixtures on in vitro nervous cells: comparison with single pesticides. Toxicology. 1996 Apr 30;108(3):201-6. The toxicity of dimethoate, azinphos-methyl, diazinon, pirimiphos methyl, organophosphorus insecticides, and benomyl (a benzimidazole fungicide) singly and in mixture was studied in a human neuroblastoma cell line, SH-SY5Y. |
0(0,0,0,0) | Details |
| 8975825 | Fossi MC, Lari L, Casini S: Interspecies variation of "B" esterases in birds: the influence of size and feeding habits. Arch Environ Contam Toxicol. 1996 Nov;31(4):525-32. An in vitro inhibition test was carried out with paraoxon and azinphos methyl oxon in order to investigate the role of equilibrium binding parameters (acetylcholinesterase/ organophosphorus compounds affinity) in determining susceptibility of the different species to parathion and azinphos methyl. |
84(1,1,1,4) | Details |
| 17097717 | Bavcon Kralj M, Franko M, Trebse P: Photodegradation of organophosphorus insecticides - investigations of products and their toxicity using gas chromatography-mass spectrometry and AChE-thermal lens spectrometric bioassay. Chemosphere. 2007 Feb;67(1):99-107. Epub 2006 Nov 13. Several other photoproducts including trimethyl esters, which are known to be AChE inhibitors and 1,2,3-benzotriazin-4 (3H)-one as a member of triazine compounds were identified in photodegraded samples of malathion, malaoxon, and azinphos-methyl. |
35(0,1,1,5) | Details |
| 8889792 | Keeble VB, Correll L, Ehrich M: Effect of laundering on ability of glove fabrics to decrease the penetration of organophosphate insecticides through in vitro epidermal systems. J Appl Toxicol. 1996 Sep-Oct;16(5):401-6. Incubations of azinphos-methyl suspensions and the in vitro epidermal systems covered with fabric indicated that both the epidermal cells and fabric provided protection against AChE inhibition caused by this OP and that the protective effects were additive, whether measured after 4 or 24 h of exposure. |
32(0,1,1,2) | Details |
| 15378568 | Reuveny H, Cohen E: Evaluation of mechanisms of azinphos-methyl resistance in the codling moth Cydia pomonella (L.). Arch Insect Biochem Physiol. 2004 Oct;57(2):92-100. In comparison to acetylcholinesterase (AChE) from susceptible adult codling moth, the enzyme of insects resistant to azinphos-methyl has low affinities (higher K (m) values) to the substrates acetylthiocholine (ATCh) and propionylthiocholine. |
31(0,1,1,1) | Details |
| 17418885 | Sturm A, Radau TS, Hahn T, Schulz R: Inhibition of rainbow trout acetylcholinesterase by aqueous and suspended particle-associated organophosphorous insecticides. Chemosphere. 2007 Jun;68(4):605-12. Epub 2007 Apr 6. The effects of two organophosphorous insecticides (OPs), chloropyrifos (CPF) and azinphos-methyl (AZP), on acetylcholinesterase (AChE) activity in rainbow trout were compared between two exposure scenarios, simulating spraydrift- and runoff-borne contamination events in the Lourens River (LR), Western Cape, South Africa. |
10(0,0,1,5) | Details |