azinphos-methyl

Identification (Source:EPA,EU)

ID 196
Name azinphos-methyl
CAS 86-50-0
IUPAC
Inchi InChI=1S/C10H12N3O3PS2/c1-15-17(18,16-2)19-7-13-10(14)8-5-3-4-6-9(8)11-12-13/h3-6H,7H2,1-2H3
CIPAC 37
EPA Code 058001
Formula C10H12N3O3PS2
SMILES S=P(OC)(OC)SCN1\N=N/c2ccccc2C1=O
Status Not Approved

Classification

Mode of Action Non-systemic, contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type Insecticide
Chemical Group Organophosphate
Classification benzotriazine organothiophosphate insecticides
heterocyclic organothiophosphate insecticides
organothiophosphate acaricides
organothiophosphate insecticides

Properties (Source:PubChem)

Molecular Weight 317.32
Physical State White crystals
AlogP 2.925
H-Bond Donor 0
H-Bond Acceptor 7
Surface Area 288.31
Polar Surface Area 130.69

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 7.15 mg l-1
Aquatic crustaceans Acute 96 hour LC50 0.00022 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.0011 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.0004 mg l-1
Birds Acute LD50 32 mg kg-1
Earthworms Acute 14 day LD50 59 mg kg-1
Fish Chronic 21 day NOEC 0.00017 mg l-1
Fish Acute 96 hour LC50 0.02 mg l-1
Honeybees Acute 48 hour LD50 0.06 μg bee-1
Mammals Acute oral LD50 9 mg kg-1
Mammals Short term dietary NOEL 5 ppm diet
Bio-concentration factor BCF 40
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
serum cholinesterase 577(5,9,12,42) Details
Acetylcholinesterase 217(1,4,7,32) Details
glutathione S transferase 116(1,2,2,6) Details
cytochrome P450 (protein family or complex) 85(1,1,1,5) Details
glutathione reductase 82(1,1,1,2) Details
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