Protein Information

Name caspase 3
Synonyms Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor…

Compound Information

Name tetramine
CAS

Reference List

PubMed Abstract RScore(About this table)
17080656 Wang Y, Shen LH, Chen WJ, Liu M, Li F, Liao ZG: [Expressions of Bcl-2 and Caspase-3 in the internal organs of rats when tetramine was administered]. Fa Yi Xue Za Zhi. 2006 Aug 15;22(4):241-4.

OBJECTIVE: To find whether Bcl-2 and Caspase-3 take part in the pathophysiological mechanism of tetramine toxification.
95(1,1,3,5) Details
11369509 Rossi L, Marchese E, Lombardo MF, Rotilio G, Ciriolo MR: Increased susceptibility of copper-deficient neuroblastoma cells to oxidative stress-mediated apoptosis. Free Radic Biol Med. 2001 May 15;30(10):1177-87.

Treatment of neuroblastoma cells with the copper chelator triethylene tetramine tetrahydrochloride induced intracellular decrease of copper content paralleled by diminished activity of the enzymes Cu, Zn superoxide dismutase, and cytochrome c oxidase.
However, molecular markers of apoptosis Bcl-2, p53, and caspase-3 were slightly affected in these cells.
2(0,0,0,2) Details
14513838 Lombardo MF, Ciriolo MR, Rotilio G, Rossi L: Prolonged copper depletion induces expression of antioxidants and triggers apoptosis in SH-SY5Y neuroblastoma cells. Cell Mol Life Sci. 2003 Aug;60(8):1733-43.


SH-SY5Y neuroblastoma cells were cultured for up to three serial passages in the presence of the copper chelator triethylene tetramine (Trien).
0(0,0,0,0) Details