Protein Information

Name c jun
Synonyms AP1; Activator protein 1; JUN; Proto oncogene c jun; Protooncogene c jun; Transcription factor AP 1; V jun avian sarcoma virus 17 oncogene homolog; c Jun…

Compound Information

Name piperonyl butoxide
CAS 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
18228000 Muguruma M, Arai K, Moto M, Nishimura J, Dewa Y, Mitsumori K: Piperonyl butoxide activates c-Jun and ATF-2 in the hepatocytes of mice. Arch Toxicol. 2008 Oct;82(10):749-53. Epub 2008 Jan 29.
224(2,4,4,4) Details
19690152 Kawai M, Saegusa Y, Jin M, Dewa Y, Nishimura J, Harada T, Shibutani M, Mitsumori K: Mechanistic study on hepatocarcinogenesis of piperonyl butoxide in mice. Toxicol Pathol. 2009;37(6):761-9. Epub 2009 Aug 18.

Early responsive genes downstream of mitogen-activated protein kinase (MAPK), such as c-fos, c-jun, c-myc, and activating transcription factor 3 (ATF3), were also up-regulated in this group.
1(0,0,0,1) Details