Protein Information

Name interleukin 4
Synonyms B cell differentiation factor gamma; B cell growth factor; B cell stimulatory factor 1; BCDF gamma; BCDFg; BCDFgamma; BCGF; BSF 1…

Compound Information

Name piperonyl butoxide
CAS 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
12755381 Diel F, Horr B, Borck H, Irman-Florjanc T: Pyrethroid insecticides influence the signal transduction in T helper lymphocytes from atopic and nonatopic subjects. Inflamm Res. 2003 Apr;52(4):154-63.


RESULTS: We demonstrated that interferon-gamma (IFN-gamma) production and expression was correlated with lymphocyte proliferation, however, interleukin-4 (IL-4) was down-regulated at the end of the 3 day culture.
3(0,0,0,3) Details
10414782 Diel F, Horr B, Borck H, Savtchenko H, Mitsche T, Diel E: Pyrethroids and piperonyl-butoxide affect human T-lymphocytes in vitro. Toxicol Lett. 1999 Jun 30;107(1-3):65-74.

In contrast to the MTT-measurements the combined agents are more effective in inhibiting interleukin-4 (IL-4)- and interferon-gamma (IFN-gamma)-production.
2(0,0,0,2) Details