Protein Information

Name mitogen activated protein kinase phosphatase 3
Synonyms DUSP 6; DUSP6; Dual specificity phosphatase 6; Dual specificity phosphatase 6 isoform b variant; Dual specificity protein phosphatase 6; Dual specificity protein phosphatase PYST1; MAP kinase phosphatase 3; MKP 3…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
17459723 Mark JK, Smith S, Hefford MA: Over-expression and refolding of MAP kinase phosphatase 3. Protein Expr Purif. 2007 Aug;54(2):253-60. Epub 2007 Mar 21.


MAP kinase phosphatase 3 (MKP3, also known as DUSP6 and PYST1) is involved in extracellular signal receptor kinase (ERK) regulation and functions as a specific phosphatase to the activated (phosphorylated) forms of ERK1 and ERK2.
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18694935 Mark JK, Aubin RA, Smith S, Hefford MA: Inhibition of mitogen-activated protein kinase phosphatase 3 activity by interdomain binding. J Biol Chem. 2008 Oct 17;283(42):28574-83. Epub 2008 Aug 11.

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