Protein Information

Name protein as
Synonyms A1 activator; PSAP; Protein C; CSAct; Cerebroside sulfatase activator; Cerebroside sulfate activator; Co beta glucosidase; Component C…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
17343730 Hytonen VP, Maatta JA, Niskanen EA, Huuskonen J, Helttunen KJ, Halling KK, Nordlund HR, Rissanen K, Johnson MS, Salminen TA, Kulomaa MS, Laitinen OH, Airenne TT: Structure and characterization of a novel chicken biotin-binding protein A (BBP-A). BMC Struct Biol. 2007 Mar 7;7:8.

2(0,0,0,2) Details
19818086 Schweikert K, Gafner F, Dell'acqua G: A bioactive complex to protect proteins from UV-induced oxidation in human epidermis. Int J Cosmet Sci. 2009 Oct 10.


We can suggest utilization of this new complex to prevent accumulation of oxidized protein as a result of skin photo-ageing and to prevent stratum corneum dehydration, skin elastosis and pigmentation formation (age spots).
1(0,0,0,1) Details
20038586 Sabaty M, Adryanczyk G, Roustan C, Cuine S, Lamouroux C, Pignol D: Coproporphyrin excretion and low thiol levels caused by point mutation in the Rhodobacter sphaeroides S-adenosylmethionine synthetase gene. J Bacteriol. 2010 Mar;192(5):1238-48. Epub 2009 Dec 28.


This point mutation is responsible for a 70% decrease in intracellular SAM content which probably affects the activities of numerous SAM-dependent enzymes such as coproporphyrinogen oxidase (HemN); uroporphyrinogen III methyltransferase (CobA), which is involved in siroheme synthesis; and molybdenum cofactor biosynthesis protein A (MoaA).
1(0,0,0,1) Details
18942891 Hemming ML, Elias JE, Gygi SP, Selkoe DJ: Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements. PLoS Biol. 2008 Oct 21;6(10):e257.


Although the proteolysis of the prototypical substrates Notch and beta-amyloid precursor protein (APP) has been intensely studied, the full spectrum of substrates and the determinants that make a transmembrane protein a substrate remain unclear.
1(0,0,0,1) Details
19504870 Lee MH, Thomas JL, Tasi SB, Liu BD, Lin HY: Formation and recognition characteristics of albumin-imprinted poly (ethylene-co-vinyl-alcohol) membranes. J Nanosci Nanotechnol. 2009 Jun;9(6):3469-77.


Surface-based molecular imprinting could offer the advantage of lower usage of template protein, as well overcoming problematic protein solubility in monomers.
1(0,0,0,1) Details
19151101 Takenawa T, Yokota A, Oda M, Takahashi H, Iwakura M: Protein oxidation during long storage: identification of the oxidation sites in dihydrofolate reductase from Escherichia coli through LC-MS and fragment studies. J Biochem. 2009 Apr;145(4):517-23. Epub 2009 Jan 16.


A peptide mapping study revealed that at least one of the methionine residues at positions 1, 16 and 20 was oxidatively modified to a methione-sulfoxide residue, while those at positions 42 and 92 were essentially unaffected.
0(0,0,0,0) Details