| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17451107 | Junghans P, Beyer M, Derno M, Petzke KJ, Kuchenmeister U, Hennig U, Jentsch W, Schwerin M: Studies on persisting effects of soy-based compared with amino acid-supplemented casein-based diet on protein metabolism and oxidative stress in juvenile pigs. Arch Anim Nutr. 2007 Apr;61(2):75-89. After switching back from SPI to CAS diet the decrease of WBPS of the test group vs. control group was of borderline significance (p = 0.061), transcript levels of hepatic gene expressions of leucine aminopeptidase, endopeptidase 24.16, glutathione-S-transferase and peptide methionine sulfoxide reductase were increased. |
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| 18692284 | Schwerin M, Kurts-Ebert B, Beyer M, Swalve H, Junghans P: Temporary consumption of diet with unbalanced amino acid pattern affects long-lasting growth retardation correlated with oxidative stress response associated gene expression in juvenile pigs. Clin Nutr. 2008 Oct;27(5):781-9. Epub 2008 Aug 8. RESULTS: Temporary feeding of SPI diet resulted in prolonged up-regulation of genes involved in oxidative/cellular stress response (glutathione-S-transferase, peptide methionine sulfoxide reductase, calnexin, organic anion transport polypeptide 2). |
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| 19033394 | Tshala-Katumbay D, Monterroso V, Kayton R, Lasarev M, Sabri M, Spencer P: Probing mechanisms of axonopathy. Toxicol Sci. 2009 Feb;107(2):482-9. Epub 2008 Nov 25. Analysis of the lumbosacral proteome by 2-dimensional differential in-gel electrophoresis and matrix-assisted laser desorption ionization time-of-flight/tandem mass spectrometry revealed 34 proteins markedly modified by 2,5-HD of which neurofilament triplet L, gelsolin, protein disulfide isomerase, glutathione S-transferase, nicotinamide adenine dinucleotide (reduced) dehydrogenase 1 alpha, kinase, and fatty acid synthase were also modified by 1,2-DAB. |
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| 19530611 | Shehab AY, Ebeid SM, El-Samak MY, Hussein NM: Detoxifying and anti-oxidant enzymes of Fasciola gigantica worms under triclabendazole sulphoxide (TCBZ-SX): an in vitro study. J Egypt Soc Parasitol. 2009 Apr;39(1):73-83. Levels of superoxide dismutase (SOD), peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), and (GSH) were measured in juvenile and adult worms incubated, without and with 15 and 50 microg/ml TCBZ-SX for 18 hours at 37 degrees C. |
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| 19343712 | Alvarez S, Berla BM, Sheffield J, Cahoon RE, Jez JM, Hicks LM: Comprehensive analysis of the Brassica juncea root proteome in response to cadmium exposure by complementary proteomic approaches. Proteomics. 2009 May;9(9):2419-31. This study determined the involvement of enzymes such as peptide methionine sulfoxide reductase and 2-nitropropane dioxygenase in alternatives redox-regulation mechanisms, as well as sulfhydrylase, glutathione-S-transferase and -conjugate membrane transporter, as essential players in the Cd hyperaccumation and tolerance of B. juncea. |
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| 17386978 | Skalova L, Krizova V, Cvilink V, Szotakova B, Storkanova L, Velik J, Lamka J: Mouflon (Ovis musimon) dicrocoeliosis: effects of parasitosis on the activities of biotransformation enzymes and albendazole metabolism in liver. Vet Parasitol. 2007 May 31;146(3-4):254-62. Epub 2007 Mar 26. In infected mouflons, a significant increase (53%) of thiobenzamide-S-oxidase (TBSO) activity, corresponding mainly to the activity of flavine monooxygenase (FMO), and significant decrease (60%) of glutathione-S-transferase (GST) activity was observed. The velocity of the formation of (+)-ABZ sulfoxide and ABZ sulfone was significantly increased. |
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| 17875331 | Mortensen AS, Arukwe A: Effects of 17alpha- on hormonal responses and xenobiotic biotransformation system of Atlantic salmon (Salmo salar). Aquat Toxicol. 2007 Nov 30;85(2):113-23. Epub 2007 Aug 17. The expression of diphosphoglucuronosyl transferase (UGT) and glutathione S-transferase class pi-like (GSTpi-like) mRNA were decreased after exposure to 50ng EE2/L at both day 3 and 7 after exposure. |
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| 20346998 | Maran E, Fernandez-Franzon M, Font G, Ruiz MJ: Effects of aldicarb and propoxur on cytotoxicity and lipid peroxidation in CHO-K1 cells. Food Chem Toxicol. 2010 Mar 24. Cytotoxic effects of aldicarb, its sulfone and sulfoxide, and propoxur, lipid peroxidation and antioxidant parameters in Chinese Hamster Ovary (CHO-K1) cells were determined. d,l-buthionine-(S,R)-sulfoximine (BSO) was assayed to determine the role of GSH in the protection against cytotoxicity. Pretreatment with 60 muM BSO, induced a significant decrease in the glutathione reductase (GR; 64 to 141%), the peroxidase (GPx; 10 to 30%) and the glutathione S-transferase (GST; 59 to 93%) activities, and it GSH levels (79-85%), while the levels significantly increased (64-78%) respect to experiment non BSO-pretreated. |
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