| Name | HDAC |
|---|---|
| Synonyms | HD7; HDAC 7; HDAC7; HD7B; HD9; HDAC; HDAC 9; HDAC7B… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18593248 | Kisseberth WC, Murahari S, London CA, Kulp SK, Chen CS: Evaluation of the effects of histone deacetylase inhibitors on cells from canine cancer cell lines. Am J Vet Res. 2008 Jul;69(7):938-45. OBJECTIVE: To determine whether exposure of canine cancer cells to histone deacetylase (HDAC) inhibitors S (+)-N--4-(3-methyl-2-phenyl-butyrylamino) benzamide (OSU-HDAC42) or suberoylanilide hydroxamic acid (SAHA) results in increased histone acetylation and decreased cell viability and whether any changes in viability involve induction of apoptosis or alterations in progression of the cell cycle. |
3(0,0,0,3) | Details |
| 19448855 | Gavin DP, Rosen C, Chase K, Grayson DR, Tun N, Sharma RP: Dimethylated 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. J Psychiatry Neurosci. 2009 May;34(3):232-7. Our objective was to ascertain whether differences exist between baseline levels of a repressive chromatin mark such as dimethylated 9 of histone 3 (H3K9me2) in patients with schizophrenia and healthy controls and whether a histone deacetylase (HDAC) inhibitor in an in vitro assay would differentially affect chromatin structure based on diagnosis. |
3(0,0,0,3) | Details |
| 19584707 | Rahim R, Strobl JS: Hydroxychloroquine, chloroquine, and regulate growth, survival, and histone acetylation in breast cancer cells. Anticancer Drugs. 2009 Sep;20(8):736-45. As an earlier study suggested that CQ, HCQ, and ATRA are breast cancer cell differentiation agents, these agents were screened in cell-free histone deacetylase (HDAC) and histone acetyltransferase (HAT) assays. |
1(0,0,0,1) | Details |