Name | methionine sulfoxide reductase B |
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Synonyms | CBS 1; CBS1; CGI 131; MSRB; MSRB 2; MSRB2; Methionine sulfoxide reductase B2; Methionine R sulfoxide reductase B… |
Name | sulfoxide |
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CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
PubMed | Abstract | RScore(About this table) | |
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19542914 | Taungjaruwinai WM, Bhawan J, Keady M, Thiele JJ: Differential expression of the antioxidant repair enzyme (MSRA and MSRB) in human skin. Am J Dermatopathol. 2009 Jul;31(5):427-31. Recently, the antioxidant repair enzymes -S-sulfoxide reductase A (MSRA) and methionine-R-sulfoxide reductase B (MSRB) were described in human epidermal keratinocytes and melanocytes. |
reductase 9(0,0,1,4) | Details |
20026324 | Pascual I, Larrayoz IM, Campos MM, Rodriguez IR: Methionine sulfoxide reductase B2 is highly expressed in the retina and protects retinal pigmented epithelium cells from oxidative damage. Exp Eye Res. 2010 Mar;90(3):420-8. Epub 2009 Dec 22. |
6(0,0,0,6) | Details |
18424444 | Cabreiro F, Picot CR, Perichon M, Castel J, Friguet B, Petropoulos I: Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage. J Biol Chem. 2008 Jun 13;283(24):16673-81. Epub 2008 Apr 17. |
6(0,0,0,6) | Details |
20236937 | Tarrago L, Laugier E, Zaffagnini M, Marchand CH, Le Marechal P, Lemaire SD, Rey P: The plant thioredoxin CDSP32 regenerates 1-CYS methionine sulfoxide reductase B activity through the direct reduction of sulfenic acid. J Biol Chem. 2010 Mar 17. |
4(0,0,0,4) | Details |
17761174 | Vieira Dos Santos C, Laugier E, Tarrago L, Massot V, Issakidis-Bourguet E, Rouhier N, Rey P: Specificity of thioredoxins and glutaredoxins as electron donors to two distinct classes of Arabidopsis plastidial reductases B. FEBS Lett. 2007 Sep 18;581(23):4371-6. Epub 2007 Aug 14. Using recombinant proteins, we show that Arabidopsis plastidial MSRB1 and MSRB2, which differ regarding the number of presumed redox-active cysteines, possess specific reductants. |
3(0,0,0,3) | Details |
19457862 | Tarrago L, Laugier E, Zaffagnini M, Marchand C, Le Marechal P, Rouhier N, Lemaire SD, Rey P: Regeneration mechanisms of Arabidopsis thaliana glutaredoxins and thioredoxins. J Biol Chem. 2009 Jul 10;284(28):18963-71. Epub 2009 May 20. In the present work we used recombinant plastidial Arabidopsis thaliana MSRB1 and MSRB2 as models for 1-Cys and 2-Cys MSRBs, respectively, to delineate the Trx- and glutaredoxin-dependent reduction mechanisms. |
reductases B by 3(0,0,0,3) | Details |
20006300 | Dhandayuthapani S, Jagannath C, Nino C, Saikolappan S, Sasindran SJ: Methionine sulfoxide reductase B (MsrB) of Mycobacterium smegmatis plays a limited role in resisting oxidative stress. Tuberculosis. 2009 Dec;89 Suppl 1:S26-32. |
2(0,0,0,2) | Details |
19874542 | Laugier E, Tarrago L, Dos Santos CV, Eymery F, Havaux M, Rey P: Arabidopsis thaliana plastidial Two MSRB isoforms, MSRB1 and MSRB2, are present in chloroplasts of Arabidopsis thaliana. |
reductases B, MSRBs, account for most leaf peptide MSR activity and are essential for growth under environmental constraints through a role in the preservation of photosystem antennae. Plant J. 2010 Jan;61(2):271-82. Epub 2009 Oct 26.3(0,0,0,3) | Details |
19415325 | Guo X, Wu Y, Wang Y, Chen Y, Chu C: OsMSRA4.1 and OsMSRB1.1, two rice plastidial In proteins, residues are especially sensitive to oxidation, leading to the formation of S- and R- diastereoisomers, and these two sulfoxides can be specifically reversed by two types of reductases (MSRs), MSRA and MSRB. |
reductases, are involved in abiotic stress responses. Planta. 2009 Jun;230(1):227-38. Epub 2009 May 5.2(0,0,0,2) | Details |
17766244 | Neiers F, Sonkaria S, Olry A, Boschi-Muller S, Branlant G: Characterization of the amino acids from Neisseria meningitidis methionine sulfoxide reductase B involved in the chemical catalysis and substrate specificity of the reductase step. J Biol Chem. 2007 Nov 2;282(44):32397-405. Epub 2007 Aug 31. The Msr family is composed of two structurally unrelated classes of enzymes named MsrA and MsrB, which display opposite stereoselectivities toward the S and R isomers of the sulfoxide function, respectively. |
1(0,0,0,1) | Details |
20167203 | Uthus EO: Determination of the specific activities of methionine sulfoxide reductase A and B by capillary electrophoresis. Anal Biochem. 2010 Feb 16. A capillary electrophoresis (CE) method for the determination of methionine sulfoxide reductase A and methionine sulfoxide reductase B activities in mouse liver is described. The method is based on detection of the 4-(dimethylamino) azobenzene-4'-sulfonyl derivative of (dabsyl Met), the product of the enzymatic reactions when either dabsyl S-sulfoxide or dabsyl R-sulfoxide is used as a substrate. |
1(0,0,0,1) | Details |
17943184 | Schallreuter KU, Rubsam K, Gibbons NC, Maitland DJ, Chavan B, Zothner C, Rokos H, Wood JM: deactivated by peroxide (H2O2) in the epidermis of patients with vitiligo. J Invest Dermatol. 2008 Apr;128(4):808-15. Epub 2007 Oct 18. Such high concentrations of H (2) O (2) oxidize residues in proteins and peptides to (R and sulfoxide diasteriomers. In this report, we show that the expression/activities of MSRA and MSRB are significantly decreased in the epidermis of patients with vitiligo compared to healthy controls. |
reductases A and B are 1(0,0,0,1) | Details |
19733575 | Ranaivoson FM, Neiers F, Kauffmann B, Boschi-Muller S, Branlant G, Favier F: Methionine sulfoxide reductase B displays a high level of flexibility. J Mol Biol. 2009 Nov 20;394(1):83-93. Epub 2009 Sep 4. MsrB are stereospecific to R epimer on the of sulfoxide. |
1(0,0,0,1) | Details |
18239417 | Park AK, Shin YJ, Moon JH, Kim YK, Hwang KY, Chi YM: Overexpression, purification, and preliminary X-ray crystallographic studies of methionine sulfoxide reductase B from Bacillus subtilis. J Microbiol Biotechnol. 2008 Jan;18(1):59-62. |
1(0,0,0,1) | Details |
19636904 | Breivik AS, Aachmann FL, Sal LS, Kim HY, Del Conte R, Gladyshev VN, Dikiy A: 1H, 15N and 13C NMR assignments of mouse methionine sulfoxide reductase B2. Biomol NMR Assign. 2008 Dec;2(2):199-201. Epub 2008 Oct 4. |
1(0,0,0,1) | Details |