| Name | androgen receptor |
|---|---|
| Synonyms | AIS; AR; Androgen receptor; DHTR; Dihydrotestosterone receptor; HUMARA; KD; NR3C4… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18639541 | Sanderson T, Renaud M, Scholten D, Nijmeijer S, van den Berg M, Cowell S, Guns E, Nelson C, Mutarapat T, Ruchirawat S: Effects of lactone derivatives on aromatase (CYP19) activity in H295R human adrenocortical and (anti) androgenicity in transfected LNCaP human prostate cancer cells. Eur J Pharmacol. 2008 Sep 28;593(1-3):92-8. Epub 2008 Jun 27. The androgen receptor is implicated in mediating hormone-dependent prostate tumor growth, and androgen antagonists are effective in the treatment of these cancers. |
2(0,0,0,2) | Details |
| 17636177 | Ishikawa T, Harada T, Kubota T, Aso T: inhibits matrix metalloproteinase-1 production in human endometrial stromal cells in vitro. Reproduction. 2007 Jun;133(6):1233-9. The present study demonstrated that the secretion and production of MMP-1 in HESCs in vitro were inhibited by through androgen receptors in a manner similar to that seen for |
1(0,0,0,1) | Details |
| 18726944 | Li W, Hwang DJ, Cremer D, Joo H, Kraka E, Kim J, Ross CR 2nd, Nguyen VQ, Dalton JT, Miller DD: Structure determination of chiral sulfoxide in diastereomeric bicalutamide derivatives. Chirality. 2009 Jun;21(6):578-83. These bicalutamide analogs are novel androgen receptor antagonists with biological activities that depend significantly on the configuration of their stereogenic centers. |
1(0,0,0,1) | Details |
| 17875331 | Mortensen AS, Arukwe A: Effects of 17alpha- on hormonal responses and xenobiotic biotransformation system of Atlantic salmon (Salmo salar). Aquat Toxicol. 2007 Nov 30;85(2):113-23. Epub 2007 Aug 17. Our data show that EE2 produced time- and concentration-specific modulation of estrogen receptor isoforms (ERalpha, ERbeta) and androgen receptor-beta (ARbeta). |
1(0,0,0,1) | Details |
| 17344101 | Mortensen AS, Arukwe A: Modulation of xenobiotic biotransformation system and hormonal responses in Atlantic salmon (Salmo salar) after exposure to tributyltin (TBT). Comp Biochem Physiol C Toxicol Pharmacol. 2007 Apr;145(3):431-41. Epub 2007 Feb 2. Our data show that TBT produced concentration-specific decrease of estrogen receptor-alpha (ERalpha), vitellogenin (Vtg), zona radiata protein (Zr-protein) and increase of estrogen receptor-beta (ERbeta) and androgen receptor-beta (ARbeta) in the hormonal pathway. |
1(0,0,0,1) | Details |