| Name | Ah receptor |
|---|---|
| Synonyms | AHR; Ah receptor; AhR; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; Dioxin receptor; Ah receptors; AhRs… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17761204 | Fried KW, Bazzi R, Levy Lopez W, Corsten C, Schramm KW, Bell DR, Rozman KK: Relationship between aryl hydrocarbon receptor-affinity and the induction of EROD activity by 2,3,7,8-tetrachlorinated phenothiazine and derivatives. Toxicol Appl Pharmacol. 2007 Oct 15;224(2):147-55. Epub 2007 Jul 19. Reported herein are semi-empirical calculations of the molecular geometry of TCDD, TCPT, TCPT-sulfoxide (TCPT-O), TCPT-sulfone (TCPT-O (2)), N-methyl-TCPT (Me-TCPT), N-methyl-TCPT-sulfoxide (Me-TCPT-O), and N-methyl-TCPT-sulfone (Me-TCPT-O (2)), the characterization of their AhR binding affinity in rat hepatic cytosol, and their ability to induce EROD activity in a rat hepatoma cell line in vitro. |
35(0,1,1,5) | Details |
| 18203687 | Bohonowych JE, Zhao B, Timme-Laragy A, Jung D, Di Giulio RT, Denison MS: Newspapers and newspaper ink contain agonists for the ah receptor. . Toxicol Sci. 2008 Apr;102(2):278-90. Epub 2008 Jan 17. |
10(0,0,0,10) | Details |
| 18936997 | Wolz J, Engwall M, Maletz S, Olsman Takner H, van Bavel B, Kammann U, Klempt M, Weber R, Braunbeck T, Hollert H: Changes in toxicity and Ah receptor agonist activity of suspended particulate matter during flood events at the rivers Neckar and Rhine - a mass balance approach using in vitro methods and chemical analysis. Environ Sci Pollut Res Int. 2008 Oct;15(7):536-53. Epub 2008 Oct 21. |
7(0,0,0,7) | Details |
| 18486664 | van Ede K, Li A, Antunes-Fernandes E, Mulder P, Peijnenburg A, Hoogenboom R: Bioassay directed identification of natural aryl hydrocarbon-receptor agonists in marmalade. Anal Chim Acta. 2008 Jun 9;617(1-2):238-45. Epub 2008 Feb 2. |
6(0,0,0,6) | Details |
| 19497421 | Vondracek J, Krcmar P, Prochazkova J, Trilecova L, Gavelova M, Skalova L, Szotakova B, Buncek M, Radilova H, Kozubik A, Machala M: The role of aryl hydrocarbon receptor in regulation of enzymes involved in metabolic activation of polycyclic aromatic hydrocarbons in a model of rat liver progenitor cells. Chem Biol Interact. 2009 Jul 15;180(2):226-37. Epub 2009 Mar 27. |
4(0,0,0,4) | Details |
| 18373956 | Arukwe A, Nordbo B: Hepatic biotransformation responses in Atlantic salmon exposed to retinoic acids and 3,3',4,4'-tetrachlorobiphenyl (PCB congener 77). Comp Biochem Physiol C Toxicol Pharmacol. 2008 May;147(4):470-82. Epub 2008 Feb 19. Aryl hydrocarbon receptor (AhR) agonists such as planar halogenated compounds are known to interfere with homeostasis in both field and laboratory studies. |
3(0,0,0,3) | Details |
| 17875331 | Mortensen AS, Arukwe A: Effects of 17alpha- on hormonal responses and xenobiotic biotransformation system of Atlantic salmon (Salmo salar). Aquat Toxicol. 2007 Nov 30;85(2):113-23. Epub 2007 Aug 17. In the xenobiotic biotransformation pathway, EE2 produced a significant increase of aryl hydrocarbon receptor-alpha (AhRalpha) at day 3 in the group given 5 ng EE2/L and AhRbeta was decreased at the same concentration at day 7. |
1(0,0,0,1) | Details |
| 17344101 | Mortensen AS, Arukwe A: Modulation of xenobiotic biotransformation system and hormonal responses in Atlantic salmon (Salmo salar) after exposure to tributyltin (TBT). Comp Biochem Physiol C Toxicol Pharmacol. 2007 Apr;145(3):431-41. Epub 2007 Feb 2. In the xenobiotic biotransformation pathway, TBT produced apparent increase and decrease at respective low and high concentration, on aryl hydrocarbon receptor-alpha (AhRalpha), AhR nuclear translocator (ARNT) and AhR repressor (AhRR) mRNA. |
1(0,0,0,1) | Details |
| 20090406 | Neis MM, Wendel A, Wiederholt T, Marquardt Y, Joussen S, Baron JM, Merk HF: Expression and induction of cytochrome p450 isoenzymes in human skin equivalents. Skin Pharmacol Physiol. 2010;23(1):29-39. Epub 2010 Jan 14. To evaluate their practicability for the investigation of xenobiotic metabolism in human skin we compared three types of organotypic skin models, acquired by purchase from different manufacturers, to a self-constructed in-house model with regard to cytochrome P450 (CYP) isoenzyme expression on mRNA and protein level and the inducibility of these enzymes by aryl hydrocarbon receptor ligands. |
1(0,0,0,1) | Details |
| 19684285 | Kim S, Dere E, Burgoon LD, Chang CC, Zacharewski TR: Comparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells. Toxicol Sci. 2009 Nov;112(1):229-44. Epub 2009 Aug 14. |
1(0,0,0,1) | Details |