| Name | p38 |
|---|---|
| Synonyms | AIMP 2; p38; AIMP2; JTV 1; JTV1; JTV1 gene; JTV1 protein; Multisynthetase complex auxiliary component p38… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17892505 | Bell JR, Eaton P, Shattock MJ: Role of p38-mitogen-activated protein kinase in ischaemic preconditioning in rat heart. Clin Exp Pharmacol Physiol. 2008 Feb;35(2):126-34. Epub 2007 Sep 24. |
9(0,0,0,9) | Details |
| 19436652 | Vikman P, Xu CB, Edvinsson L: Lipid-soluble cigarette smoking particles induce expression of inflammatory and extracellular-matrix-related genes in rat cerebral arteries. Vasc Health Risk Manag. 2009;5(1):333-41. Epub 2009 Apr 8. In addition, the activity of three mitogen-activated protein kinases (p38, ERK 1/2 and SAPK/JNK) and their downstream transcription factors (ATF-2, Elk-1 and c-Jun) were examined. |
3(0,0,0,3) | Details |
| 19782097 | Datta S, Mazumder S, Ghosh D, Dey S, Bhattacharya S: Low concentration of arsenic could induce caspase-3 mediated head kidney macrophage apoptosis with JNK-p38 activation in Clarias batrachus. Toxicol Appl Pharmacol. 2009 Dec 15;241(3):329-38. Epub 2009 Sep 24. |
3(0,0,0,3) | Details |
| 17344341 | Kammerer B, Scheible H, Albrecht W, Gleiter CH, Laufer S: Pharmacokinetics of ML3403 ({4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H--4-yl]-pyridin-2-yl}-( 1-phenylethyl)-amine), a 4-Pyridinylimidazole-type p38 mitogen-activated protein kinase inhibitor. Drug Metab Dispos. 2007 Jun;35(6):875-83. Epub 2007 Mar 7. In addition, pharmacokinetics of ML3403 were evaluated in male and female Wistar rats after oral gavage, showing a fast and high conversion to its active sulfoxide metabolite ML3603. |
3(0,0,0,3) | Details |
| 17395177 | Kishioka T, Iida C, Fujii K, Nagae R, Onishi Y, Ichi I, Kojo S: Effect of on oxidative stress, activation of mitogen activated protein kinase and necrosis caused by thioacetamide in the rat liver. Eur J Pharmacol. 2007 Jun 14;564(1-3):190-5. Epub 2007 Mar 12. Phosphorylated p38 MAPK (mitogen activated protein kinase) was significantly decreased 24 h after administration of thioacetamide. |
1(0,0,0,1) | Details |
| 19012662 | Martin-Renedo J, Mauriz JL, Jorquera F, Ruiz-Andres O, Gonzalez P, Gonzalez-Gallego J: induces cell cycle arrest and apoptosis in hepatocarcinoma HepG2 cell line. J Pineal Res. 2008 Nov;45(4):532-40. In addition, JNK 1,-2 and -3 and p38, members of the MAPK family, were upregulated by treatment. |
1(0,0,0,1) | Details |
| 18645497 | Ito T, Omori K, Rawson J, Todorov I, Asari S, Kuroda A, Shintaku J, Itakura S, Ferreri K, Kandeel F, Mullen Y: Improvement of canine islet yield by donor pancreas infusion with a p38MAPK inhibitor. Transplantation. 2008 Jul 27;86(2):321-9. BACKGROUND: The activation of p38 mitogen-activated protein kinases (MAPK) is implicated in cold ischemia-reperfusion injury of donor organs. |
1(0,0,0,1) | Details |
| 20084046 | Omori K, Todorov I, Shintaku J, Rawson J, Al-Abdullah IH, Higgins LS, Medicherla S, Kandeel F, Mullen Y: P38alpha-Selective Mitogen-Activated Protein Kinase Inhibitor for Improvement of Cultured Human Islet Recovery. Pancreas. 2010 Jan 13. RESULTS:: Expression of p38 and phosphorylated p38 in islets increased during culture. |
1(0,0,0,1) | Details |
| 20091890 | Hui C, Like W, Yan F, Tian X, Qiuyan W, Lifeng H: S-allyl- sulfoxide inhibits tumor necrosis factor-alpha induced monocyte adhesion and intercellular cell adhesion molecule-1 expression in human umbilical vein endothelial cells. Anat Rec. 2010 Mar;293(3):421-30. |
0(0,0,0,0) | Details |