Protein Information

Name beta catenin
Synonyms Beta catenin; CTNNB; CTNNB 1; CTNNB1; Catenin beta; Catenin beta 1; OK/SW cl.35; PRO2286…

Compound Information

Name sulfoxide
CAS 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole

Reference List

PubMed Abstract RScore(About this table)
19814781 Kennedy KA, Porter T, Mehta V, Ryan SD, Price F, Peshdary V, Karamboulas C, Savage J, Drysdale TA, Li SC, Bennett SA, Skerjanc IS: Retinoic acid enhances skeletal muscle progenitor formation and bypasses inhibition by bone morphogenetic protein 4 but not dominant negative beta-catenin. BMC Biol. 2009 Oct 8;7:67.


By chromatin immunoprecipitation, RA receptors (RARs) bound directly to regulatory regions in the Wnt3a, Pax3, and Meox1 genes and RA activated a beta-catenin-responsive promoter in aggregated P19 cells.
2(0,0,0,2) Details
19785986 Zhuo L, Gong J, Yang R, Sheng Y, Zhou L, Kong X, Cao K: Inhibition of proliferation and differentiation and promotion of apoptosis by cyclin L2 in mouse embryonic carcinoma P19 cells. Biochem Biophys Res Commun. 2009 Dec 18;390(3):451-7. Epub 2009 Sep 26.


In addition, real-time PCR analysis revealed that expression of Wnt and beta-catenin was suppressed and GSK3beta was induced in the CCNL2-overexpressing P19 cells.
1(0,0,0,1) Details
19530134 Khalfallah O, Rouleau M, Barbry P, Bardoni B, Lalli E: Dax-1 knockdown in mouse embryonic stem cells induces loss of pluripotency and multilineage differentiation. Stem Cells. 2009 Jul;27(7):1529-37.


Here, we show that Dax-1 expression is affected by differentiating treatments and pharmacological activation of beta-catenin-dependent transcription in mouse ES cells.
1(0,0,0,1) Details
20091315 Roura S, Farre J, Hove-Madsen L, Prat-Vidal C, Soler-Botija C, Galvez-Monton C, Vilalta M, Bayes-Genis A: Exposure to cardiomyogenic stimuli fails to transdifferentiate human umbilical cord blood-derived mesenchymal stem cells. Basic Res Cardiol. 2010 May;105(3):419-30. Epub 2010 Jan 21.


Expression of cardiomyocyte-specific proteins and beta-catenin were assessed by quantitative RT-PCR, immunofluorescence and Western blot.
1(0,0,0,1) Details
18545679 Kami D, Shiojima I, Makino H, Matsumoto K, Takahashi Y, Ishii R, Naito AT, Toyoda M, Saito H, Watanabe M, Komuro I, Umezawa A: Gremlin enhances the determined path to cardiomyogenesis. PLoS One. 2008 Jun 11;3(6):e2407.


Furthermore, BMP2 inhibited Wnt/beta-catenin signaling that promoted CL6 cardiomyogenesis.
1(0,0,0,1) Details