| Name | peroxisome proliferator activated receptor |
|---|---|
| Synonyms | NR1C1; PPAR; PPAR alpha; PPARA; PPARalpha; Peroxisome proliferator activated receptor; Peroxisome proliferator activated receptor alpha; hPPAR… |
| Name | sulfoxide |
|---|---|
| CAS | 5-[2-(octylsulfinyl)propyl]-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18713766 | Wolf CJ, Takacs ML, Schmid JE, Lau C, Abbott BD: Activation of mouse and human peroxisome proliferator-activated receptor alpha by perfluoroalkyl acids of different functional groups and chain lengths. Toxicol Sci. 2008 Nov;106(1):162-71. Epub 2008 Aug 18. |
9(0,0,0,9) | Details |
| 18836674 | Still K, Grabowski P, Mackie I, Perry M, Bishop N: The peroxisome proliferator activator receptor alpha/delta agonists and bezafibrate upregulate osteoblast differentiation and induce periosteal bone formation in vivo. Calcif Tissue Int. 2008 Oct;83(4):285-92. Epub 2008 Oct 4. The aims of this study were to determine the effects of PPARalpha/delta agonists on bone in vitro and in vivo. |
5(0,0,0,5) | Details |
| 19237170 | Minutoli L, Antonuccio P, Polito F, Bitto A, Squadrito F, Irrera N, Nicotina PA, Fazzari C, Montalto AS, Di Stefano V, Romeo C, Altavilla D: Peroxisome proliferator activated receptor beta/delta activation prevents extracellular regulated kinase 1/2 phosphorylation and protects the testis from ischemia and reperfusion injury. J Urol. 2009 Apr;181(4):1913-21. Epub 2009 Feb 23. |
3(0,0,0,3) | Details |
| 19151258 | Bulhak AA, Jung C, Ostenson CG, Lundberg JO, Sjoquist PO, Pernow J: PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway. Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H719-27. Epub 2009 Jan 16. The ligands of peroxisome proliferator-activated receptor-alpha (PPAR-alpha) reduce ischemia-reperfusion injury in nondiabetic animals. |
2(0,0,0,2) | Details |
| 19474210 | Liu Y, Shi J, Lu J, Meng G, Zhu H, Hou Y, Yin Y, Zhao S, Ding B: Activation of peroxisome proliferator-activated receptor-gamma potentiates pro-inflammatory cytokine production, and and somatotropic changes of weaned pigs after Escherichia coli lipopolysaccharide challenge. Innate Immun. 2009 Jun;15(3):169-78. Our previous study demonstrated mRNA and protein expression of peroxisome proliferator-activated receptor-g (PPAR-g) in the immune system of weaned pigs. |
4(0,0,0,4) | Details |
| 19946680 | Thevis M, Moller I, Thomas A, Beuck S, Rodchenkov G, Bornatsch W, Geyer H, Schanzer W: Characterization of two major urinary metabolites of the PPARdelta-agonist GW1516 and implementation of the drug in routine doping controls. Anal Bioanal Chem. 2010 Apr;396(7):2479-91. Epub 2009 Nov 28. Since January 2009, the list of prohibited substances and methods of doping as established by the World Anti-Doping Agency includes new therapeutics such as the peroxisome-proliferator-activated receptor (PPAR)-delta agonist GW1516, which is categorized as a gene doping substance. These allowed the identification and characterization of mono-oxygenated and bisoxygenated metabolites (sulfoxide and sulfone, respectively) as supported by high-resolution/high-accuracy mass spectrometry with higher-energy collision-induced dissociation, tandem mass spectrometry, and nuclear magnetic resonance spectroscopy. |
1(0,0,0,1) | Details |
| 20167109 | Galuppo M, Di Paola R, Mazzon E, Genovese T, Crisafulli C, Paterniti I, Cuzzocrea E, Bramanti P, Kapoor A, Thiemermann C, Cuzzocrea S: Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study. J Inflamm. 2010 Feb 18;7:12. ABSTRACT: BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)-beta/delta is a nuclear receptor transcription factor that regulates gene expression in many important biological processes. |
1(0,0,0,1) | Details |
| 19423011 | Kim SL, Kim EM, Cheong SJ, Lee CM, Kim DW, Jeong HJ, Lim ST, Sohn MH, Yim CY: The effect of PPAR-gamma agonist on (18) F-FDG uptake in tumor and macrophages and tumor cells. Nucl Med Biol. 2009 May;36(4):427-33. Epub 2009 Mar 26. Thus, the present study was undertaken to investigate the potential of using PPAR-gamma's uptake ability as a diagnostic tool to differentiate between macrophage and tumor cells. |
1(0,0,0,1) | Details |