16484214 |
Carr JF, Hamburg DM, Gregory ST, Limbach PA, Dahlberg AE: Effects of streptomycin resistance mutations on posttranslational modification of ribosomal protein S12. J Bacteriol. 2007 May;189(10):3876-83. Epub 2007 Mar 23. Ribosomal protein S12 contains a highly conserved aspartic acid residue that is posttranslationally beta-methylthiolated. Using mass spectrometry, we have determined the modification states of several S12 mutants of Thermus thermophilus and conclude that beta-methylthiolation is not a determinant of the streptomycin phenotype. |
82(1,1,1,2) |