| 12700320 |
Liang TW, Balcer LJ, Solomon D, Messe SR, Galetta SL: Supranuclear gaze palsy and opsoclonus after Diazinon poisoning. J Neurol Neurosurg Psychiatry. 2003 May;74(5):677-9.
A 52 year old man developed a supranuclear gaze palsy and opsoclonus after Diazinon poisoning. The diagnosis was confirmed by low plasma and red blood cell cholinesterase activity and urine mass spectroscopy. Saccadic control may be mediated in part by acetylcholine. Opsoclonus in the setting of organophosphate intoxication may occur as a result of cholinergic excess which overactivates the fastigial nuclei. |
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