9743476 |
Guilherme A, Reis-Silva C, Moraes-Albuquerque JH, Oliveira MM, Vieyra A: A novel phosphorylated lipid counteracts activation of the renal plasma membrane (Ca2+ + Mg2+) ATPase by endogenous phosphatidylinositol-4-phosphate. Biosci Rep. 1998 Apr;18(2):79-89. The plasma membrane (Ca2+ + Mg2+) ATPase is activated by acidic phospholipids in reconstituted systems. In this report it is shown that reversible phosphorylation of endogenous phosphatidylinositol regulates the renal plasma membrane (Ca2+ + Mg2+) ATPase, and that a novel phosphorylated lipid that can be isolated from the same membrane strongly counteracts the stimulatory effect of phosphatidylinositol-4-phosphate. |
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