| ID | 47 |
|---|---|
| Name | cytochrome P450 (protein family or complex) |
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| ID | 183 |
|---|---|
| Name | lindane |
| CAS | (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) |
|---|---|---|
| 1727005 | Piekoszewski W, Brandys J, Lipniak M: Studies on sex related differences in elimination of in the rat after pretreatment with phenobarbital, chrysene, Aroclor 1254 or lindane. Acta Pol Pharm. 1991;48(1-2):9-12. Cytochrome P-450 in liver microsomes plays a central role as a drug metabolizing enzyme. The sex-dependent differences in the properties of cytochrome P-450 have been extensively studied using liver microsomes, and marked differences have been found in microsomal metabolism of xenobiotic. Effect of pretreatment with phenobarbital, chrysene, lindane and polychlorinated biphenyls (Aroclor 1254) on the elimination in male and female rats was studied. Levels of were measured spectrophotometrically. |
2(0,0,0,2) |