Protein Information

ID 3
Name phospholipase A2
Synonyms 14 3 3 protein zeta/delta; Phospholipase A2; KCIP 1; Protein kinase C inhibitor protein 1; 14 3 3 protein/cytosolic phospholipase A2; 14 3 3 zeta; FAS; Factor activating exoenzyme S…

Compound Information

ID 1468
Name HCH
CAS 1,2,3,4,5,6-hexachlorocyclohexane

Reference

PubMed Abstract RScore(About this table)
1651249 Yamada K, Saltarelli MD, Coyle JT: [3H] hemicholinium-3 binding in rats with status epilepticus induced by lithium chloride and pilocarpine. Eur J Pharmacol. 1991 Apr 3;195(3):395-7.
The specific binding of [3H] hemicholinium-3 ([3H] HCh-3) and high-affinity [3H] choline uptake were measured in rats with status epilepticus induced by lithium and pilocarpine. The specific binding of [3H] HCh-3 in cortex and hippocampus from rats with status epilepticus increased to 2- to 3-fold of control while the striatal [3H] HCh-3 binding increased minimally. Scatchard analyses revealed that the observed changes resulted from an increase in Bmax of [3H] HCh-3 binding. High-affinity [3H] choline uptake remained unchanged. These results further implicate phospholipase A2 in the regulation of [3H] HCh-3 binding sites.
31(0,1,1,1)