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Ridlington JW, Chapman DE, Boese BL, Johnson VG, Randall R: Petroleum refinery wastewater induction of the hepatic mixed-function oxidase system in Pacific staghorn sculpin. Arch Environ Contam Toxicol. 1982;11(1):123-7. Induction of hepatic microsomal cytochrome P450 and aldrin epoxidase was observed in the estuarine sculpin (Leptocottus armatus), following in vivo exposure to Class B petroleum refinery effluent from two West Coast refineries. The data demonstrate the presence and inducibility of the mixed-function oxidase system in Leptocottus armatus. Differences in the extent of mixed-function oxidase induction between the two effluents may be related to differences in wastewater chemistry. |
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