Protein Information

ID 3716
Name PSCP
Synonyms BRCA 1; BRCC1; p220; BRCA1; BRCAI; BRCC 1; Breast cancer type 1 susceptibility protein; IRIS…

Compound Information

ID 202
Name chlorpyrifos
CAS

Reference

PubMed Abstract RScore(About this table)
1384807 Dong K, Scott JG: Synergism of chlorpyrifos against the German cockroach, Blattella germanica. Med Vet Entomol. 1992 Jul;6(3):241-3.
Of fifteen compounds tested as synergists for chlorpyrifos against susceptible and resistant strains of Blattella germanica, the German cockroach, eleven were active against the resistant strain but only seven were synergistic against the susceptible strain. Overall, the most effective synergist was S,S,S-tributyl phosphorotrithioate (DEF) followed by phenyl saligenin cyclic phosphonate (PSCP) and two substituted N,N-dimethylcarbamates: SK-102 and SK-37. The most effective synergist for overcoming chlorpyrifos resistance was SK-37 which reduced the resistance ratio by 3.2-fold. Four other synergists which reduced chlorpyrifos resistance, in order of their effectiveness, were: SK-102 > PSCP > DEF > tridiphane. The potential usefulness of these synergists for German cockroach control is discussed.
32(0,1,1,2)