Protein Information

ID 33
Name ATPase
Synonyms ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1…

Compound Information

ID 268
Name cypermethrin
CAS cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate

Reference

PubMed Abstract RScore(About this table)
19823759 Prashanth MS, David M: Impact of cypermethrin on Na (+)-K (+), Ca (2+) and Mg (2+) ATPases in Indian major carp, Cirrhinus mrigala (Hamilton). Bull Environ Contam Toxicol. 2010 Jan;84(1):80-4. Epub 2009 Oct 13.
Activities of ATPase in different organs of Cirrhinus mrigala exposed to cypermethrin with lethal (5.13 microg/L) and sublethal (1.02 microg/L) concentration was investigated. Decrease of Na (+)-K (+)-ATPase activity was observed in gills, liver and muscle to about 60.22%, 22.13% and 48.89% respectively, by lethal concentration. Whereas in sublethal concentration activity was increased to about 7.84%, 10.70% and 5.96%. Similarly, in case of Mg (2+)-ATPases activity as 57.61%, 48.82% and 28.59% for lethal and for sublethal it was 10.15%, 4.64% and 11.92%. Ca (2+)-ATPase activity was observed to be 55.24%, 41.66% and 47.66% by lethal and for sublethal it was 8.02%, 24.89% and 6.47%.
8(0,0,1,3)