Protein Information

ID 1106
Name K12
Synonyms K12; Protein K12; SECTM 1; SECTM1; Secreted and transmembrane 1; Secreted and transmembrane protein 1; Secreted and transmembrane protein 1 precursor; Protein K12s…

Compound Information

ID 355
Name oxytetracycline
CAS

Reference

PubMed Abstract RScore(About this table)
16690225 Schelz Z, Molnar J, Hohmann J: Antimicrobial and antiplasmid activities of essential oils. Fitoterapia. 2006 Jun;77(4):279-85. Epub 2006 May 11.
The antimicrobial and antiplasmid activities of essential oils (orange oil, eucalyptus oil, fennel oil, geranium oil, juniper oil, peppermint oil, rosemary oil, purified turpentine oil, thyme oil, Australian tea tree oil) and of menthol, the main component of peppermint oil, were investigated. The antimicrobial activities were determined on the Gram (+) Staphylococcus epidermidis and the Gram (-) Escherichia coli F'lac K12 LE140, and on two yeast Saccharomyces cerevisiae 0425 delta/1 and 0425 52C strains. The antiplasmid activities were investigated on E. coli F'lac bacterial strain. Each of the oils exhibited antimicrobial activity and three of them antiplasmid action. The interaction of peppermint oil and menthol with the antibiotics was studied on the same bacterial strain with the checkerboard method. Peppermint oil and menthol displayed additive synergy with oxytetracycline. A new mechanism of plasmid curing was established for one of the oil components.
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