Protein Information

ID 47
Name cytochrome P450 (protein family or complex)
Synonyms cytochrome P450; cytochrome P 450; CYP450; CYP 450

Compound Information

ID 483
Name hexachlorobenzene
CAS 1,2,3,4,5,6-hexachlorobenzene

Reference

PubMed Abstract RScore(About this table)
4015737 Lissner R, Brunner W, Bolsen K, Merk H, Goerz G: Influence of N-acetylcysteine on the hexachlorobenzene induced porphyria in rats. Arzneimittelforschung. 1985;35(4):713-5.
The course of hexachlorobenzene (HCB) induced porphyria was not influenced by the concomitant administration of N-acetylcysteine (NAC) to the animals: urinary excretion of total porphyrins and porphyrin precursors as well as the hepatic aminolevulinate synthase activities were not influenced by NAC treatment. In addition, no differences could be shown between the HCB and the HCB/NAC combination group concerning the hepatic cytochrome P-450 contents or the P-450 dependent enzyme activities.
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