| ID | 450 |
|---|---|
| Name | demethylase |
| Synonyms | DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases… |
| ID | 182 |
|---|---|
| Name | endosulfan |
| CAS | 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide |
| PubMed | Abstract | RScore(About this table) |
|---|---|---|
| 45318 | Agarwal DK, Seth PK, Gupta PK: Effect of endosulfan on drug metabolizing enzymes and lipid peroxidation in rat. J Environ Sci Health C. 1978;13(1):49-62. The influence of endosulfan, a chlorinated hydrocarbon insecticide, on rat hepatic drug metabolizing enzymes and lipid peroxidation has been explored in the present study. Total liver weight was significantly increased after endosulfan administration at both dose levels (2.5 and 5.0 mg/kg body weight) without affecting body weight or 9000 x g supernatant protein content. There was a marked increase in the activity of aminopyrine-N-demethylase, hydroxylase, amino-transferase and spontaneous lipid peroxidation. In all cases the increase was dose dependent. |
1(0,0,0,1) |