P14

General Information (Source: NCBI Gene,UniProt)

Text mining Term P14
UniProt ID TCP4_RAT
Name p14
PC4
Activated RNA polymerase II transcriptional coactivator p15
SUB1 homolog
Positive cofactor 4
Gene Names Sub1
Taxonomy Rattus norvegicus

General annotation

Function General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity).
Subcellular location Nucleus (By similarity).

Gene Ontology

GO:0006351 transcription, DNA-dependent BP

Sequence

>gi|57526804|ref|NP_001009618.1| activated RNA polymerase II transcriptional coactivator p15 [Rattus norvegicus]
MPKSKELVSSSSSGSDSDSEVEKKLKRKKQVVPEKPVKKQKPGESSRALASSKQSSSSRDDNMFQIGKMR
YVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSRNOT00000015443
UniGene Rn.8706
PDB
RefSeq NP_001009618.1
Pfam PF02229