NMDA receptor (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term NMDA receptor (protein family or complex)
UniProt ID CKG_CONGE
Name Conotoxin GV
Conantokin-G
CGX-1007
Con-G
Sleeper peptide
Gene Names
Taxonomy Conus geographus

General annotation

Function Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors. This toxin is selective for the NR2B/GRIN2B subunit. Induces sleep-like symptoms in young mice and hyperactivity in older mice.
Subcellular location Secreted.

Gene Ontology

GO:0046872 metal ion binding MF
GO:0035792 other organism postsynaptic membrane CC
GO:0008200 ion channel inhibitor activity MF

Sequence

>gi|253723039|pdb|1ONU|A Chain A, Nmda Receptor Antagonist, Conantokin-G, Nmr, 17 Structures
GEXXLQXNQXLIRXKSNX

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Database Cross Reference

Ensembl Gene
UniGene
PDB 1AD7
1AWY
1ONU
RefSeq
Pfam