hormone receptor

General Information (Source: NCBI Gene,UniProt)

Text mining Term hormone receptor
UniProt ID GNRHR_OCTVU
Name oct-GnRHR
GnRH-R
GnRH receptor
Gonadotropin-releasing hormone receptor
Gene Names GNRHR
Taxonomy Octopus vulgaris

General annotation

Function Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle- stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol- calcium second messenger system. Ligand interaction triggers steroidogenesis in spermatozoa and follicles. Appears to be involved in contraction of the radula retractor muscle.
Subcellular location Cell membrane; Multi-pass membrane protein.

Gene Ontology

GO:0005886 plasma membrane CC
GO:0004930 G-protein coupled receptor activity MF
GO:0016021 integral to membrane CC

Sequence

>gi|122003017|sp|Q2V2K5.1|GNRHR_OCTVU RecName: Full=Gonadotropin-releasing hormone receptor; Short=GnRH receptor; Short=GnRH-R; Short=oct-GnRHR
MDYLNDSMFNNMTYNITSTPLPDAPRFDNVYVSKLCVLGTVFVISFFGNTLVIIQIFRIRGSRSTIQSLI
LNLAIADLMVSFFNILMDIIWSATVEWLAGNTMCKIMKYLTVFGLHLSTYITVSIALDRCFAILSPMSRS
KAPLRVRIMITMAWVLSAIFSIPQAVIFQEQRKMFRQGMFHQCRDSYNALWQKQLYSASSLILLFVIPLI
IMVTSYLLILKTIVKTSRQFHDTPISPTSMSCYSVNHGQIRTHLFERARKRSSRMSAVIVAAFILCWTPY
YIIFLGFAFFQWDNSRTVIYFFTLGTSNCMLNPLIYGAFTIYKVHRGRSGSANSPSGTRLMIMVNKRGRS
TTTTTNRMSGSGRRQLTTGQTITQCASLTNPHQPVRPSPGINSTTSPNGKMPTKPPG

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF00001