norflurazon

Identification (Source:EPA,EU)

ID 1066
Name norflurazon
CAS 27314-13-2
IUPAC
Inchi InChI=1S/C12H9ClF3N3O/c1-17-9-6-18-19(11(20)10(9)13)8-4-2-3-7(5-8)12(14,15)16/h2-6,17H,1H3
CIPAC 8233
EPA Code 105801
Formula C12H9ClF3N3O
SMILES FC(F)(F)c1cc(ccc1)N2/N=C\C(=C(\Cl)C2=O)NC
Status Not Approved

Classification

Mode of Action Selective, absorbed by roots and translocated. Bleaching: inhibition of carotenoid biosynthesis.
Pesticide Type Herbicide
Chemical Group Pyridazinone
Classification pyridazinone herbicides

Properties (Source:PubChem)

Molecular Weight 303.7
Physical State White to greyish-brown crystalline powder
AlogP 2.023
H-Bond Donor 1
H-Bond Acceptor 3
Surface Area 259.81
Polar Surface Area 44.7

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 0.0176 mg l-1
Aquatic crustaceans Acute 96 hour LC50 2.29 mg l-1
Aquatic invertebrates Acute 48 hour EC50 15 mg l-1
Aquatic plants Acute 7 day EC50, biomass 0.086 mg l-1
Birds Acute LD50 2150 mg kg-1
Earthworms Acute 14 day LD50 1000 mg kg-1
Fish Acute 96 hour LC50 8.1 mg l-1
Honeybees Acute 48 hour LD50 235 μg bee-1
Mammals Acute oral LD50 > 5000 mg kg-1
Mammals Short term dietary NOEL 19 mg kg-1
Bio-concentration factor BCF 28
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
b protein 145(1,3,3,5) Details
cytochrome P450 (protein family or complex) 87(1,1,1,7) Details
CYP1A1 86(1,1,1,6) Details
hydroxypyruvate reductase 84(1,1,1,4) Details
protoporphyrinogen oxidase 81(1,1,1,1) Details
factor is 31(0,1,1,1) Details
protein a 31(0,1,1,1) Details
CYP2B6 12(0,0,1,7) Details
superoxide dismutase 11(0,0,1,6) Details
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