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pyriproxyfen

Identification (Source:EPA,EU)

ID	1428
Name	pyriproxyfen
CAS	95737-68-1
IUPAC
Inchi	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3
CIPAC	715
EPA Code
Formula	C20H19NO3
SMILES	O(c1ncccc1)C(COc3ccc(Oc2ccccc2)cc3)C
Status	Approved

Classification

Mode of Action	A juvenile hormone mimic. Inhibits insect maturation process
Pesticide Type	Insecticide, Veterinary treatment
Chemical Group	Unclassified
Classification	juvenile hormone mimics

Properties (Source:PubChem)

Molecular Weight	321.37
Physical State	White granule solid
AlogP	4.771
H-Bond Donor	0
H-Bond Acceptor	4
Surface Area	309.5
Polar Surface Area	40.58

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.056 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	0.047 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.4 mg l-1
Aquatic plants	Acute	7 day	EC50, biomass	> 0.18 mg l-1
Birds	Acute		LD50	> 1906 mg kg-1
Birds	Short term dietary		LC50/LD50	> 863 mg/kg bw/day
Earthworms	Acute	14 day	LD50	> 500 mg kg-1
Fish	Acute	96 hour	LC50	> 0.27 mg l-1
Honeybees	Acute	48 hour	LD50	> 100 μg bee-1
Mammals	Acute oral		LD50	> 5000 mg kg-1
Mammals	Short term dietary		NOEL	> 24 mg kg-1
Mammals	Short term dietary		NOEL	> 400 ppm diet
Sediment dwelling organisms	Chronic	28 day	NOEC, sediment	0.01 mg kg-1
	Bio-concentration factor		CT50	0.9 days
	Bio-concentration factor		BCF	1379

Related targets

Target Name	RScore (About this table)
CRS	62(0,2,2,2)	Details
hemoglobin (protein family or complex)	41(0,1,1,11)	Details
protein is	32(0,1,1,2)	Details
protein as	31(0,1,1,1)	Details
cytochrome P450 (protein family or complex)	13(0,0,2,3)	Details
C18	8(0,0,1,3)	Details
cytochrome P450 monooxygenases	6(0,0,1,1)	Details

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