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tebufenozide

Identification (Source:EPA,EU)

ID	1437
Name	tebufenozide
CAS	112410-23-8
IUPAC
Inchi	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)
CIPAC	724
EPA Code
Formula	C22H28N2O2
SMILES	O=C(c1cc(cc(c1)C)C)N(NC(=O)c2ccc(cc2)CC)C(C)(C)C
Status	Approved

Classification

Mode of Action	Accelerates molting, mainly stomach action
Pesticide Type	Insecticide
Chemical Group	Diacylhydrazine
Classification	moulting hormone agonists

Properties (Source:PubChem)

Molecular Weight	352.47
Physical State	Off-white powder
AlogP	4.923
H-Bond Donor	1
H-Bond Acceptor	2
Surface Area	378.64
Polar Surface Area	49.41

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.23 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	0.82 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	3.8 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.029 mg l-1
Birds	Acute		LD50	> 2150 mg kg-1
Earthworms	Acute	14 day	LD50	> 1000 mg kg-1
Fish	Acute	96 hour	LC50	3.0 mg l-1
Fish	Chronic	21 day	NOEC	0.71 mg l-1
Honeybees	Acute	48 hour	LD50	> 234 μg bee-1
Mammals	Acute oral		LD50	> 5000 mg kg-1
Mammals	Short term dietary		NOEL	5.5 mg kg-1
	Bio-concentration factor		CT50	2 days
	Bio-concentration factor		BCF	70

Related targets

Target Name	RScore (About this table)
glutathione S transferase	91(1,1,1,11)	Details
hormone receptor	19(0,0,0,19)	Details
p65	8(0,0,1,3)	Details
P60	8(0,0,1,3)	Details
LC20	6(0,0,1,1)	Details
chitinase	5(0,0,0,5)	Details
helicase	4(0,0,0,4)	Details
cytochrome P450 (protein family or complex)	4(0,0,0,4)	Details

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