clothianidin

Identification (Source:EPA,EU)

ID 1455
Name clothianidin
CAS 210880-92-5 (formerly 205510-53-8)
IUPAC
Inchi
CIPAC 738
EPA Code 44309
Formula C6H8ClN5O2S
SMILES Clc1ncc(s1)CN/C(=N/C)N[N+]([O-])=O
Status Approved

Classification

Mode of Action Translaminar and root systemic activity. Acetylcholine receptor (nAChR) agonist.
Pesticide Type Insecticide, Metabolite
Chemical Group Neonicotinoid
Classification nitroguanidine nicotinoid insecticides
thiazole insecticides

Properties (Source:PubChem)

Molecular Weight 249.7
Physical State Colourless powder
AlogP 2.625
H-Bond Donor 2
H-Bond Acceptor 5
Surface Area 237.03
Polar Surface Area 123.37

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 55 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.12 mg l-1
Aquatic invertebrates Acute 48 hour EC50 > 40 mg l-1
Aquatic plants Acute 7 day EC50, biomass 121 mg l-1
Birds Short term dietary LC50/LD50 > 752 mg/kg bw/day
Birds Acute LD50 430 mg kg-1
Earthworms Chronic 14 day NOEC, reproduction 2.5 mg kg-1
Earthworms Acute 14 day LD50 13.21 mg kg-1
Fish Chronic 21 day NOEC 20.0 mg l-1
Fish Acute 96 hour LC50 > 104.2 mg l-1
Honeybees Acute 48 hour LD50 0.004 μg bee-1
Mammals Acute oral LD50 > 500 mg kg-1
Sediment dwelling organisms Acute 96 hour LC50 0.029 mg l-1
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.00072 mg kg-1
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
acetylcholine receptor (protein family or complex) 54(0,1,3,14) Details
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