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alpha-cypermethrin

Identification (Source:EPA,EU)

ID	269
Name	alpha-cypermethrin
CAS	67375-30-8
IUPAC
Inchi	InChI=1S/2C22H19Cl2NO3/c2*1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h2*3-12,17-18,20H,1-2H3/t2*17-,18+,20-/m10/s1
CIPAC	454
EPA Code
Formula	C22H19Cl2NO3
SMILES	Cl/C(Cl)=C/C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C
Status	Approved

Classification

Mode of Action	Non-systemic with contact and stomach action. Sodium channel modulator.
Pesticide Type	Insecticide, Veterinary treatment
Chemical Group	Pyrethroid
Classification	pyrethroid ester acaricides pyrethroid ester insecticides

Properties (Source:PubChem)

Molecular Weight	416.30
Physical State	Colourless crystals
AlogP	5.304
H-Bond Donor	0
H-Bond Acceptor	4
Surface Area	391.36
Polar Surface Area	59.32

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.1 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.0003 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.00003 mg l-1
Birds	Acute		LD50	> 2025 mg kg-1
Earthworms	Acute	14 day	LD50	> 100 mg kg-1
Fish	Chronic	21 day	NOEC	0.00003 mg l-1
Fish	Acute	96 hour	LC50	0.0028 mg l-1
Honeybees	Acute	48 hour	LD50	0.033 μg bee-1
Mammals	Acute oral		LD50	57 mg kg-1
Mammals	Short term dietary		NOEL	200 ppm diet
Mammals	Short term dietary		NOEL	5 mg kg-1
	Bio-concentration factor		BCF	1204
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
cytochrome P450 monooxygenases	83(1,1,1,3)	Details
p70	39(0,1,2,4)	Details
IL 12 (protein family or complex)	39(0,1,2,4)	Details
chloride channel (protein family or complex)	31(0,1,1,1)	Details
cytochrome P450 (protein family or complex)	9(0,0,0,9)	Details
CA3	8(0,0,1,3)	Details
cork 1	7(0,0,1,2)	Details
Cl 2	6(0,0,0,6)	Details

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