famoxadone

Identification (Source:EPA,EU)

ID 575
Name famoxadone
CAS 131807-57-3
IUPAC
Inchi InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3
CIPAC 594
EPA Code 113202
Formula C22H18N2O4
SMILES O=C2OC(C(=O)N2Nc1ccccc1)(c4ccc(Oc3ccccc3)cc4)C
Status Approved

Classification

Mode of Action Protectant with residual activity, interferes with plant respiratory system
Pesticide Type Fungicide
Chemical Group Oxazole
Classification dicarboximide fungicides
oxazole fungicides

Properties (Source:PubChem)

Molecular Weight 374.39
Physical State Pale cream powder
AlogP 4.882
H-Bond Donor 1
H-Bond Acceptor 5
Surface Area 338.99
Polar Surface Area 67.87

Structure



ChemMapper Search Option (Docunmentation of ChemMapper)

3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 0.022 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.012 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.0037 mg l-1
Aquatic plants Acute 7 day EC50, biomass 0.081 mg l-1
Birds Short term dietary LC50/LD50 > 5620 mg/kg feed
Birds Acute LD50 > 2250 mg kg-1
Earthworms Acute 14 day LD50 470 mg kg-1
Fish Acute 96 hour LC50 0.011 mg l-1
Fish Chronic 21 day NOEC 0.0014 mg l-1
Honeybees Acute 48 hour LD50 > 25 μg bee-1
Mammals Acute oral LD50 > 5000 mg kg-1
Mammals Short term dietary NOEL 3.3 mg kg-1
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.01 mg kg-1
Bio-concentration factor BCF 3000
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
cytochrome bc1 359(4,5,5,9) Details
ubiquinol cytochrome c reductase (protein family or complex) 81(1,1,1,1) Details
cytochrome c 1 32(0,1,1,2) Details
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