Name | BAK1 |
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Synonyms | Apoptosis regulator BAK; BAK; BAK 1; BAK LIKE; BAK1; BCL2 antagonist killer 1; BCL2L7; Bcl 2 homologous antagonist/killer… |
Name | brassinolide |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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19452453 | Chang IF, Curran A, Woolsey R, Quilici D, Cushman JC, Mittler R, Harmon A, Harper JF: Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Proteomics. 2009 Jun;9(11):2967-85. The identification here of 121 putative clients provides support for in vivo 14-3-3 interactions with a diverse array of proteins, including those involved in: (i) Ion transport, such as a K (+) channel (GORK), a Cl (-) channel (CLCg), Ca (2+) channels belonging to the glutamate receptor family (1.2, 2.1, 2.9, 3.4, 3.7); (ii) hormone signaling, such as ACC synthase (isoforms ACS-6, -7 and -8 involved in ethylene synthesis) and the brassinolide receptors BRI1 and BAK1; (iii) transcription, such as 7 WRKY family transcription factors; (iv) metabolism, such as phosphoenol pyruvate carboxylase; and (v) lipid signaling, such as phospholipase D (beta and gamma). |
81(1,1,1,1) | Details |
17583510 | Kemmerling B, Schwedt A, Rodriguez P, Mazzotta S, Frank M, Qamar SA, Mengiste T, Betsuyaku S, Parker JE, Mussig C, Thomma BP, Albrecht C, de Vries SC, Hirt H, Nurnberger T: The BRI1-associated kinase 1, BAK1, has a brassinolide-independent role in plant cell-death control. Curr Biol. 2007 Jul 3;17(13):1116-22. Epub 2007 Jun 21. |
64(0,2,2,4) | Details |
20103591 | Schulze B, Mentzel T, Jehle AK, Mueller K, Beeler S, Boller T, Felix G, Chinchilla D: Rapid heteromerization and phosphorylation of ligand-activated plant transmembrane receptors and their associated kinase BAK1. J Biol Chem. 2010 Mar 26;285(13):9444-51. Epub 2010 Jan 26. Similarly, brassinolide induces BAK1 phosphorylation within seconds. |
36(0,1,1,6) | Details |
19704727 | Kemmerling B, Nurnberger T: Brassinosteroid-independent functions of the BRI1-associated kinase BAK1/SERK3. Plant Signal Behav. 2008 Feb;3(2):116-8. BAK1 is known to interact with the brassinosteroid receptor, BRI1, and thereby facilitates plant growth and development in a brassinolide (BL)-dependent manner.4,5 Surprisingly, the cell death-related phenotype in bak1 mutants is brassinolide-independent. |
35(0,1,1,5) | Details |
19532123 | Song L, Shi QM, Yang XH, Xu ZH, Xue HW: Membrane steroid-binding protein 1 (MSBP1) negatively regulates brassinosteroid signaling by enhancing the endocytosis of BAK1. Cell Res. 2009 Jul;19(7):864-76. The transmembrane receptor BRI1 can directly bind to brassinolide (BL), and BAK1 interacts with BRI1 to enhance the BRI1-mediated BR signaling. |
35(0,1,1,5) | Details |
18667726 | Albrecht C, Russinova E, Kemmerling B, Kwaaitaal M, de Vries SC: Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASE proteins serve brassinosteroid-dependent and -independent signaling pathways. Plant Physiol. 2008 Sep;148(1):611-9. Epub 2008 Jul 30. One member of this family, BRASSINOSTEROID INSENSITIVE1 (BRI1)-ASSOCIATED KINASE1 (BAK1), also known as SERK3, is the coreceptor of the brassinolide (BR)-perceiving receptor BRI1, a function that is BR dependent and partially redundant with SERK1. |
32(0,1,1,2) | Details |
19400727 | Boller T, Felix G: A renaissance of elicitors: perception of microbe-associated molecular patterns and danger signals by pattern-recognition receptors. Annu Rev Plant Biol. 2009;60:379-406. Upon treatment with flagellin, FLS2 forms a heteromeric complex with BAK1, an LRR-RK that also acts as coreceptor for the brassinolide receptor BRI1. |
31(0,1,1,1) | Details |
19277500 | Yun HS, Bae YH, Lee YJ, Chang SC, Kim SK, Li J, Nam KH: Analysis of phosphorylation of the BRI1/BAK1 complex in arabidopsis reveals amino acid residues critical for receptor formation and activation of BR signaling. Mol Cells. 2009 Feb;27(2):183-90. Epub 2009 Feb 20. |
8(0,0,0,8) | Details |
18694562 | Wang X, Kota U, He K, Blackburn K, Li J, Goshe MB, Huber SC, Clouse SD: Sequential transphosphorylation of the BRI1/BAK1 receptor kinase complex impacts early events in brassinosteroid signaling. Dev Cell. 2008 Aug;15(2):220-35. |
7(0,0,0,7) | Details |
20108170 | Jeong YJ, Shang Y, Kim BH, Kim SY, Song JH, Lee JS, Lee MM, Li J, Nam KH: BAK7 displays unequal genetic redundancy with BAK1 in brassinosteroid signaling and early senescence in arabidopsis. Mol Cells. 2010 Jan 21. Furthermore, the sensitivity of transgenic plants overexpressing BAK7 to brassinazole, a biosynthetic inhibitor of brassinolide (BL), did not change compared to that of wild-type plants. |
7(0,0,0,7) | Details |
17027118 | Wang L, Xu YY, Li J, Powell RA, Xu ZH, Chong K: Transgenic rice plants ectopically expressing AtBAK1 are semi-dwarfed and hypersensitive to 24-epibrassinolide. J Plant Physiol. 2007 May;164(5):655-64. Epub 2006 Oct 4. Brassinosteroid insensitive1 (BRI1)-assocaiated receptor kinase (BAK1) is one of the key components in the BR signal transduction pathway due to its direct association with the BR receptor, BRI1. |
4(0,0,0,4) | Details |
12150929 | Li J, Wen J, Lease KA, Doke JT, Tax FE, Walker JC: BAK1, an Arabidopsis LRR receptor-like protein kinase, interacts with BRI1 and modulates brassinosteroid signaling. Cell. 2002 Jul 26;110(2):213-22. |
4(0,0,0,4) | Details |
16699538 | Wang ZY, Wang Q, Chong K, Wang F, Wang L, Bai M, Jia C: The brassinosteroid signal transduction pathway. Cell Res. 2006 May;16(5):427-34. Recent studies have demonstrated that BR binding to the extracellular domain of BRI1 induces kinase activation and dimerization with another receptor kinase, BAK1. |
2(0,0,0,2) | Details |
17003466 | Karlova R, de Vries SC: Advances in understanding brassinosteroid signaling. Sci STKE. 2006 Sep 26;2006(354):pe36. BR binding to the extracellular domain of the receptor BRI1 induces kinase activation and hetero-oligomerization with the second transmembrane kinase BAK1. |
1(0,0,0,1) | Details |
17470144 | Kim TW, Lee SM, Joo SH, Yun HS, Lee Y, Kaufman PB, Kirakosyan A, Kim SH, Nam KH, Lee JS, Chang SC, Kim SK: Elongation and gravitropic responses of Arabidopsis roots are regulated by brassinolide and IAA. Plant Cell Environ. 2007 Jun;30(6):679-89. Exogenously applied brassinolide (BL) increased both gravitropic curvature and length of primary roots of Arabidopsis at low concentration (10 (-10) M), whereas at higher concentration, BL further increased gravitropic curvature while it inhibited primary root growth. Interestingly, IAA treatment to the roots of bri1-301 and bak1 plants or of plants pretreated with a BL biosynthetic inhibitor, brassinazole, increased their sensitivity to gravity, while these treatments for the BL-hypersensitive transgenic plants, BRI1-GFP and 35S-BAK1, were less effective. |
1(0,0,0,1) | Details |
16857903 | Wang X, Chory J: Brassinosteroids regulate dissociation of BKI1, a negative regulator of BRI1 signaling, from the plasma membrane. Science. 2006 Aug 25;313(5790):1118-22. Epub 2006 Jul 20. BKI1 is a substrate of BRI1 kinase and limits the interaction of BRI1 with its proposed coreceptor, BAK1, suggesting that BKI1 prevents the activation of BRI1. |
1(0,0,0,1) | Details |