Protein Information

Name G protein
Synonyms G gamma I; Guanine nucleotide binding protein 2; G protein; GNG 2; GNG2; GNGT 2; GNGT2; Guanine nucleotide binding protein gamma 2…

Compound Information

Name brassinolide
CAS

Reference List

PubMed Abstract RScore(About this table)
15181210 Chen JG, Pandey S, Huang J, Alonso JM, Ecker JR, Assmann SM, Jones AM: GCR1 can act independently of heterotrimeric G-protein in response to brassinosteroids and gibberellins in Arabidopsis seed germination. Plant Physiol. 2004 Jun;135(2):907-15. Epub 2004 Jun 4.

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12068128 Ullah H, Chen JG, Wang S, Jones AM: Role of a heterotrimeric G protein in regulation of Arabidopsis seed germination. Plant Physiol. 2002 Jun;129(2):897-907.

Furthermore, gpa1 seeds are completely insensitive to brassinolide rescue of germination when the level of GA in seeds is reduced.
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19649188 Oki K, Kitagawa K, Fujisawa Y, Kato H, Iwasaki Y: Function of alpha subunit of heterotrimeric G protein in brassinosteroid response of rice plants. Plant Signal Behav. 2009 Feb;4(2):126-8.

The application of 24-epi-brassinolide (24-epiBL) to T65d1 expressing Q223L still resulted in elongation of the coleoptile and, in fact, it was enhanced over the wild-type plant (WT) level in a concentration dependent manner.
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19420799 Oki K, Inaba N, Kitano H, Takahashi S, Fujisawa Y, Kato H, Iwasaki Y: Study of novel d1 alleles, defective mutants of the alpha subunit of heterotrimeric G-protein in rice. Genes Genet Syst. 2009 Feb;84(1):35-42.

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19036785 Oki K, Inaba N, Kitagawa K, Fujioka S, Kitano H, Fujisawa Y, Kato H, Iwasaki Y: Function of the alpha subunit of rice heterotrimeric G protein in brassinosteroid signaling. Plant Cell Physiol. 2009 Jan;50(1):161-72. Epub 2008 Nov 26.

Decreased sensitivity to 24-epi-brassinolide (24-epiBL) in the T65d1 mutant was observed in many processes examined, e.g. in the inhibition of root growth and the promotion of coleoptile elongation.
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18499742 Gao Y, Wang S, Asami T, Chen JG: Loss-of-function mutations in the Arabidopsis heterotrimeric G-protein alpha subunit enhance the developmental defects of brassinosteroid signaling and biosynthesis mutants. Plant Cell Physiol. 2008 Jul;49(7):1013-24. Epub 2008 May 22.


Taken together, these results provided the first genetic evidence that G-protein- and BR-mediated pathways may be converged to modulate cell proliferation in a cell/tissue-specific manner.
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13677471 Yang G, Matsuoka M, Iwasaki Y, Komatsu S: A novel brassinolide-enhanced gene identified by cDNA microarray is involved in the growth of rice. Plant Mol Biol. 2003 Jul;52(4):843-54.

BL effect in the d1 mutant rice was much weaker than that in its wild-type control, indicating that heterotrimeric G protein may be a component of BRs signaling.
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11402196 Li H, Shen JJ, Zheng ZL, Lin Y, Yang Z: The Rop GTPase switch controls multiple developmental processes in Arabidopsis. Plant Physiol. 2001 Jun;126(2):670-84.

G proteins are universal molecular switches in eukaryotic signal transduction.
The rop2 transgenic plants also displayed altered responses to the exogenous application of several hormones, such as abscisic acid-mediated seed dormancy, auxin-dependent lateral shoot initiation, and brassinolide-mediated hypocotyl elongation.
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