| 19604308 |
Vanhoutte VJ, McAulay KA, McCarrell E, Turner M, Crawford DH, Haque T: Cytolytic mechanisms and T-cell receptor Vbeta usage by ex vivo generated Epstein-Barr virus-specific cytotoxic T lymphocytes. Immunology. 2009 Aug;127(4):577-86.
Cytotoxicity of CTL was significantly inhibited by concanamycin A (P < 0.0001) and ethylene glycol-bis tetraacetic acid (P < 0.0001), indicating that a calcium and perforin-mediated exocytosis pathway with the release of granzyme B was the principal cytotoxic mechanism. |
32(0,1,1,2) |
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