| Name | prostate specific membrane antigen |
|---|---|
| Synonyms | FGCP; GCP2; FOLH; FOLH 1; FOLH1; Folate hydrolase 1; Folylpoly gamma glutamate carboxypeptidase; GCPII… |
| Name | ethylene |
|---|---|
| CAS | ethene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19488725 | Gu F, Langer R, Farokhzad OC: Formulation/preparation of functionalized nanoparticles for in vivo targeted drug delivery. Methods Mol Biol. 2009;544:589-98. Here we describe the preparation of drug-encapsulated nanoparticles formulated with biocompatible and biodegradable poly (D: ,L: -lactic-co--block-poly (ethylene glycol) (PLGA-b-PEG) copolymer and surface functionalized with the A10 2-fluoropyrimidine ribonucleic acid aptamers that recognize the extracellular domain of prostate-specific membrane antigen (PSMA), a well-characterized antigen expressed on the surface of prostate cancer cells. |
82(1,1,1,2) | Details |
| 20217595 | Chan JM, Valencia PM, Zhang L, Langer R, Farokhzad OC: Polymeric nanoparticles for drug delivery. Methods Mol Biol. 2010;624:163-75. In this chapter, we describe the methods of (1) preparation and characterization of drug-encapsulated polymeric NPs formulated with biocompatible and biodegradable poly (D,L-lactic-co--poly (ethylene glycol) (PLGA-b-PEG) copolymers; (2) surface functionalization of the polymeric NPs with the A10 2'-fluoropyrimidine ribonucleic acid (RNA) aptamers that recognize the prostate-specific membrane antigen (PSMA) on prostate cancer cells; and (3) evaluation of the binding properties of these targeted polymeric NPs to PSMA-expressing prostate cancer cells in vitro and in vivo. |
81(1,1,1,1) | Details |