| Name | P85 |
|---|---|
| Synonyms | ARHGEF 7; PAK3; p85; p50; ARHGEF7; BETA PIX; COOL 1; COOL1… |
| Name | ethylene |
|---|---|
| CAS | ethene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19957968 | Krupka TM, Solorio L, Wilson RE, Wu H, Azar N, Exner AA: Formulation and characterization of echogenic lipid-pluronic nanobubbles. Mol Pharm. 2010 Feb 1;7(1):49-59. In this work, we present a novel strategy for formulation of nanosized, echogenic lipid bubbles by incorporating the surfactant Pluronic, a triblock copolymer of ethylene oxide copropylene oxide coethylene oxide into the formulation. Five Pluronics (L31, L61, L81, L64 and P85) with a range of molecular weights (M (w): 1100 to 4600 Da) were incorporated into the lipid shell either before or after lipid film hydration and before addition of perfluorocarbon gas. |
1(0,0,0,1) | Details |
| 20053933 | Price TO, Farr SA, Yi X, Vinogradov S, Batrakova E, Banks WA, Kabanov AV: Transport across the blood-brain barrier of pluronic leptin. . J Pharmacol Exp Ther. 2010 Apr;333(1):253-63. Epub 2010 Jan 6. Chemical modification of polypeptides with amphiphilic poly (ethylene oxide)-poly (propylene oxide) block copolymers (Pluronic) is a promising technology to improve efficiency of delivery of polypeptides to the brain. In the present study, we determined the effects of Pluronic P85 (P85) with intermediate hydrophilic-lipophilic balance conjugated with leptin via a degradable SS bond [leptin (ss)-P85] on food intake, clearance, stability, and BBB uptake. |
4(0,0,0,4) | Details |
| 19596093 | Garripelli VK, Kim JK, Namgung R, Kim WJ, Repka MA, Jo S: A novel thermosensitive polymer with pH-dependent degradation for drug delivery. Acta Biomater. 2010 Feb;6(2):477-85. Epub 2009 Jul 22. A class of thermosensitive biodegradable multiblock copolymers with acid-labile acetal linkages were synthesized from Pluronic triblock copolymers (Pluronic P85 and P104) and di-(ethylene glycol) divinyl ether. |
32(0,1,1,2) | Details |
| 19963266 | Sahay G, Gautam V, Luxenhofer R, Kabanov AV: The utilization of pathogen-like cellular trafficking by single chain block copolymer. Biomaterials. 2010 Mar;31(7):1757-64. Epub 2009 Dec 5. Amphiphilic triblock copolymer, poly (ethylene oxide)-b-poly (propylene oxide)-b-poly (ethylene oxide), Pluronic P85, is unexpectedly shown to utilize sophisticated cellular trafficking mechanisms and enter brain microvessel endothelial cells and primary neurons that are poorly penetrable. |
6(0,0,1,1) | Details |
| 20074598 | Batrakova EV, Li S, Brynskikh AM, Sharma AK, Li Y, Boska M, Gong N, Mosley RL, Alakhov VY, Gendelman HE, Kabanov AV: Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers. J Control Release. 2010 Jan 13. Pluronic (triblock copolymers of poly (ethylene oxide) (PEO) and poly (propylene oxide) (PPO), PEO-b-PPO-b-PEO) were previously shown to sensitize MDR tumors to antineoplastic agents. This study uses animal models of Lewis lung carcinoma (3LL-M27) and T-lymphocytic leukemia (P388/ADR and P388) derived solid tumors to delineate mechanisms of sensitization of MDR tumors by Pluronic P85 (P85) in vivo. |
4(0,0,0,4) | Details |
| 20000432 | Clover B, Hammouda B: SANS from P85/-d under Pressure. Langmuir. 2009 Dec 10. Pluronics are triblock copolymers of poly (ethylene oxide)-poly (propylene oxide)-poly (ethylene oxide). |
3(0,0,0,3) | Details |