| 20128995 |
Liu Z, Liu S, Niu G, Wang F, Liu S, Chen X: Optical imaging of integrin alphavbeta3 expression with near-infrared fluorescent RGD dimer with tetra (ethylene glycol) linkers. Mol Imaging. 2010 Feb;9(1):21-9.
We report here the noninvasive visualization of tumor integrin alphavbeta3 expression by using near-infrared fluorescence (NIRF) imaging of an IRDye800-labeled new cyclic RGD (arginine-glycine-aspartic acid) dimer with tetra (ethylene glycol) (PEG4) linkers (ie, E [PEG4-c (RGDfK)] 2, PEG4 = 15-amino-4,7,10,13-tetraoxapentadecanoic acid) in a U87MG tumor model. |
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