Protein Information

Name Cyp 3
Synonyms CP33; CYP3; HLP; CYP3A; CP34; CYP 3A4; CYP 3; CYP3A3…

Compound Information

Name ethylene
CAS ethene

Reference List

PubMed Abstract RScore(About this table)
19679108 Zharikova OL, Fokina VM, Nanovskaya TN, Hill RA, Mattison DR, Hankins GD, Ahmed MS: Identification of the major human hepatic and placental enzymes responsible for the biotransformation of glyburide. Biochem Pharmacol. 2009 Dec 15;78(12):1483-90. Epub 2009 Aug 11.

The data revealed that the major hepatic isozymes responsible for the formation of each metabolite are as follows: CYP3A4 (ethylene-hydroxylated glyburide (M5), 3-trans-(M3) and 2-trans-(M4) cyclohexyl glyburide); CYP2C9 (M1, M2a (4-cis-) and M2b); CYP2C8 (M1 and M2b); and CYP2C19 (M2a).
31(0,1,1,1) Details
20136131 Leitao EM, van der Eide EF, Romero PE, Piers WE, McDonald R: Kinetic and thermodynamic analysis of processes relevant to initiation of olefin metathesis by ruthenium phosphonium alkylidene catalysts. J Am Chem Soc. 2010 Mar 3;132(8):2784-94.

Seven 16-electron zwitterionic catalyst precursors of general formula (H (2) IMes)(Cl)(3) Ru=C (H) P (R (1))(2) R (2) (R (1) = R (2) = C (6) H (11), C (5) H (9), i-C (3) H (7), 1-Cy (3)-Cl, 1-Cyp (3)-Cl, 1-(i) Pr (3)-Cl; R (1) = C (6) H (11), R (2) = CH (2) CH (3), 1-EtCy (2)-Cl; R (1) = C (6) H (11), R (2) = CH (3), 1-MeCy (2)-Cl; R (1) = i-C (3) H (7), R (2) = CH (2) CH (3), 1-Et (i) Pr (2)-Cl; R (1) = i-C (3) H (7), R (2) = CH (3), 1-Me (i) Pr (2)-Cl) were prepared.
A more complex initiation process was observed in that the rates were accelerated by catalytic amounts of ethylene produced in the reaction with o-isopropoxystyrene.
1(0,0,0,1) Details