| Name | alkaline phosphatase |
|---|---|
| Synonyms | ALP 1; Alkaline phosphatase; ALPG; ALPPL; ALPPL 2; ALPPL2; GCAP; Germ cell alkaline phosphatase… |
| Name | ethylene |
|---|---|
| CAS | ethene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19944190 | Kroeze RJ, Helder MN, Roos WH, Wuite GJ, Bank RA, Smit TH: The effect of ethylene oxide, glow discharge and electron beam on the surface characteristics of poly (l-lactide-co-caprolactone) and the corresponding cellular response of adipose stem cells. Acta Biomater. 2009 Nov 26. The alkaline phosphatase activity was significantly higher for the ethylene oxide sterilized PLCL sheet. |
6(0,0,1,1) | Details |
| 20005327 | Shedge HY, Creager SE: Evaluation of non-specific binding suppression schemes for neutravidin and alkaline phosphatase at the surface of reticulated vitreous carbon electrodes. Anal Chim Acta. 2010 Jan 11;657(2):154-62. Epub . Electrodes functionalized with and poly (ethylene glycol) (PEG) showed low NSB and high SB (when capture ligands were included in the modification scheme) in comparison with unmodified electrodes and RVC electrodes modified in other ways. |
2(0,0,0,2) | Details |
| 19565188 | Liu ZM, Lee SY, Sarun S, Peschel D, Groth T: Immobilization of poly (ethylene imine) on poly (L: -lactide) promotes MG63 cell proliferation and function. J Mater Sci Mater Med. 2009 Jun 30. Cell morphologies, immuno-fluorescence staining, cell proliferation by lactate dehydrogenase assay and cell differentiation by alkaline phosphatase assay were utilized to assess the biocompatibility of the modified PLLA using osteoblast cell line MG63. |
1(0,0,0,1) | Details |
| 19995620 | Xu W, Ma J, Jabbari E: Material properties and osteogenic differentiation of marrow stromal cells on fiber-reinforced laminated hydrogel nanocomposites. Acta Biomater. 2009 Dec 6. Layers of electrospun poly (l-lactide) fiber mesh coated with a poly (lactide-co-ethylene oxide (PLEOF) hydrogel precursor solution were stacked and pressed together, and crosslinked to produce a laminated fiber-reinforced composite. At days 14 and 21, alkaline phosphatase (ALPase) activity of the laminates was significantly higher than those of the fiber mesh and hydrogel. |
1(0,0,0,1) | Details |
| 19586040 | Yang XZ, Sun TM, Dou S, Wu J, Wang YC, Wang J: Block copolymer of polyphosphoester and poly modified surface for enhancing osteoblast adhesion, proliferation, and function. Biomacromolecules. 2009 Aug 10;10(8):2213-20. In this study, block copolymers of poly and poly (ethyl ethylene (PLLA-b-PEEP) were synthesized and used to modify the PLLA surface via a spin-coating process, to understand whether surface modification with polyphosphoester-based polymer will be osteoinductive for potential bone tissue engineering applications. Moreover, cellular alkaline phosphatase activity and mineral depositions were also promoted by PEEP modification. |
1(0,0,0,1) | Details |
| 19775136 | Zhang P, Henthorn DB: Fabrication of high-capacity biomolecular carriers from dispersible single-walled carbon nanotube-polymer composites. Langmuir. 2009 Oct 20;25(20):12308-14. In this work, we successfully used an ultraviolet light initiated "graft from" polymerization method to fabricate polymer functionalized carbon nanotubes (PFCNTs) with pendant chains of various functionalities, including poly (ethylene glycol) chains to boost dispersibility and pendant epoxy groups for protein conjugate sites. A model enzyme, alkaline phosphatase, was used to study biomolecule loading efficiency as well as the retention of enzyme activity. |
1(0,0,0,1) | Details |
| 20158316 | Wang G, Kucharski C, Lin X, Uludag H: Bisphosphonate-coated BSA nanoparticles lack bone targeting after systemic administration. J Drug Target. 2010 Feb 16. A polymeric conjugate of polyethyleneimine-graft-poly (ethylene glycol) and 2-(3-mercaptopropylsulfanyl)-ethyl-1,1-bisphosphonic acid (PEI-PEG-thiolBP) was prepared and used for surface coating of bovine serum albumin (BSA) nanoparticles (NPs) designed for bone-specific delivery of bone morphogenetic protein-2 (BMP-2). On the basis of an alkaline phosphatase (ALP) induction assay, the NP-encapsulated BMP-2 displayed full retention of its bioactivity, except for BMP-2 in PEI-coated NPs. |
1(0,0,0,1) | Details |
| 20345129 | Betz MW, Yeatts AB, Richbourg WJ, Caccamese JF, Coletti DP, Falco EE, Fisher JP: Macroporous Hydrogels Upregulate Osteogenic Signal Expression and Promote Bone Regeneration. Biomacromolecules. 2010 Mar 26. In particular, we have proposed a tissue engineering approach for orbital bone repair based on a cyclic acetal biomaterial formed from 5-ethyl-5-(hydroxymethyl)-beta,beta-dimethyl-1,3-dioxane-2- diacrylate (EHD) and poly (ethylene glycol) diacrylate (PEGDA). This upregulation of BMP-2 expression is associated by a more rapid hMSC differentiation, as measured by alkaline phosphatase expression. |
1(0,0,0,1) | Details |
| 20197126 | Guo X, Liao J, Park H, Saraf A, Raphael RM, Tabata Y, Kasper FK, Mikos AG: Effects of TGF-beta3 and preculture period of osteogenic cells on the chondrogenic differentiation of rabbit marrow mesenchymal stem cells encapsulated in a bilayered hydrogel composite. Acta Biomater. 2010 Mar 1. In this work, injectable, biodegradable hydrogel composites of crosslinked oligo (poly (ethylene glycol) and gelatin microparticles (MPs) were used to fabricate a bilayered osteochondral construct. In the osteogenic layer, cells maintained their alkaline phosphatase activity during the coculture; however, mineralization was delayed by the presence of TGF-beta3. |
1(0,0,0,1) | Details |
| 20088700 | Zhang Y, Reddy VJ, Wong SY, Li X, Su B, Ramakrishna S, Lim CT: Enhanced Biomineralization in Osteoblasts on a Novel Electrospun Biocomposite Nanofibrous Substrate of Hydroxyapatite/Collagen/ Tissue Eng Part A. 2010 Mar 1. We show herein that Col-doped HAp/CTS biocomposite (i.e., HAp/Col/CTS) containing 27.8 wt% HAp nanoparticles, 7.2 wt% Col, and 57.8 wt% CTS can be successfully electrospun into nanofibrous form through using small amount (7.2 wt%) of ultrahigh-molecular-weight poly (ethylene oxide) as the fiber-forming additive. In comparison with different controls, significant increments in osteoblast proliferation, alkaline phosphatase expression, and mineral deposition were observed. |
1(0,0,0,1) | Details |
| 19857481 | Nishigaki T, Teramura Y, Suemori H, Iwata H: Cryopreservation of primate embryonic stem cells with chemically-defined solution without Me2SO. Cryobiology. 2010 Apr;60(2):159-64. Epub 2009 Oct 24. We have cryopreserved cynomolgus and human ES cells by the vitrification method, using a chemically-defined (Me (2) SO)-free and serum-free medium composed of Euro-Collins solution as a base medium and 40% (v/v) ethylene glycol (EG) and 10% (w/v) polyethylene glycol (PEG) as cryoprotectants. After the cryopreservation and thawing cycle, hES cells were easily cultured and expressed undifferentiated cell markers such as Nanog, Oct-4, SSEA-4, and alkaline phosphatase activity after several subculturing steps. |
1(0,0,0,1) | Details |
| 20222105 | Sung K, Kamiya N, Kawata N, Kamiya S, Goto M: Functional glass surface displaying a glutamyl donor substrate for transglutaminase-mediated protein immobilization. Biotechnol J. 2010 Mar 10. Validation of the Z-QG modified glass surfaces with recombinant enhanced green fluorescent proteins revealed that the insertion of a di (ethylene glycol) linker between the terminal Z-QG moiety and the base not only enhances enzymatic protein immobilization efficiency but also decreases nonselective protein adsorption. A bacterial alkaline phosphatase fused with a K-tag at the N terminus was also successfully immobilized to the designed glass surface, suggesting that the chemically modified glass surface displaying a spatially controlled glutamyl donor substrate is a potential platform for MTG-mediated fabrication of protein-based solid biomaterials. |
1(0,0,0,1) | Details |
| 19878992 | Zhang S, Kucharski C, Doschak MR, Sebald W, Uludag H: Polyethylenimine-PEG coated albumin nanoparticles for BMP-2 delivery. Biomaterials. 2010 Feb;31(5):952-63. Epub 2009 Oct 29. In this study, we report a nanoparticulate (NP) system for BMP-2 delivery based on bovine serum albumin (BSA) NPs stabilized with a poly (ethylene glycol) modified polyethylenimine (PEI-PEG) coating. The bioactivity of the encapsulated BMP-2 and the toxicity of PEI-PEG coated NPs were examined by the alkaline phosphatase (ALP) induction assay and the MTT assay, respectively, using human C2C12 cells. |
1(0,0,0,1) | Details |
| 20039599 | Nandakumar A, Yang L, Habibovic P, van Blitterswijk C: Coated Electrospun Fiber Matrices as Scaffolds for Bone Tissue Engineering. Langmuir. 2009 Dec 29. In this study, we applied a biomimetic coating method to provide electrospun scaffolds from a block copolymer-poly (ethylene oxide terephthalate)-poly (buthylene terephthalate), with a layer to improve their bioactivity in bone tissue engineering. |
0(0,0,0,0) | Details |