| Name | folate receptor |
|---|---|
| Synonyms | Adult folate binding protein; FBP; FOLR; FOLR 1; FOLR1; FR alpha; FRa; FRalpha… |
| Name | ethylene |
|---|---|
| CAS | ethene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19770010 | Zheng Y, Song X, Darby M, Liang Y, He L, Cai Z, Chen Q, Bi Y, Yang X, Xu J, Li Y, Sun Y, Lee RJ, Hou S: Preparation and characterization of -poly (ethylene glycol)-grafted-trimethylchitosan for intracellular transport of protein through folate receptor-mediated endocytosis. J Biotechnol. 2010 Jan 1;145(1):47-53. Epub . |
83(1,1,1,3) | Details |
| 19507896 | Kim D, Gao ZG, Lee ES, Bae YH: In vivo evaluation of doxorubicin-loaded polymeric micelles targeting folate receptors and early endosomal pH in drug-resistant ovarian cancer. Mol Pharm. 2009 Sep-Oct;6(5):1353-62. |
3(0,0,0,3) | Details |
| 20117198 | Morris VB, Sharma CP: mediated derivative of quaternised as a gene delivery vector. Int J Pharm. 2010 Apr 15;389(1-2):176-85. Epub 2010 Feb 1. targeted gene delivery vectors showed enhanced accumulation in folate receptor expressing tumor model. mediated targeting was induced by conjugating poly (ethylene glycol)- (PEG-FA) on modified polymer having low molecular weight of 15 kDa and high degree of quaternisation (HTFP15-H). |
2(0,0,0,2) | Details |
| 19643472 | Prabaharan M, Grailer JJ, Pilla S, Steeber DA, Gong S: Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery. Biomaterials. 2009 Oct;30(29):5757-66. Epub 2009 Jul 29. -conjugated unimolecular micelles based on amphiphilic hyperbranched block copolymer, Boltorn H40-poly (l--doxorubicin)-b-poly (ethylene glycol)/FA-conjugated poly (ethylene glycol) (H40-P (LA-DOX)-b-PEG-OH/FA), were synthesized as a carrier for tumor-targeted drug delivery. Cellular uptake of the H40-P (LA-DOX)-b-PEG-OH/FA micelles was found to be higher than that of the H40-P (LA-DOX)-b-PEG-OH micelles because of the folate-receptor-mediated endocytosis, thereby providing higher cytotoxicity against the 4T1 mouse mammary carcinoma cell line. |
1(0,0,0,1) | Details |
| 19674777 | Prabaharan M, Grailer JJ, Pilla S, Steeber DA, Gong S: Gold nanoparticles with a monolayer of doxorubicin-conjugated amphiphilic block copolymer for tumor-targeted drug delivery. Biomaterials. 2009 Oct;30(30):6065-75. Epub 2009 Aug 12. Gold (Au) nanoparticles (NPs) stabilized with a monolayer of -conjugated poly -doxorubicin)-b-poly (ethylene glycol) copolymer (Au-P (LA-DOX)-b-PEG-OH/FA) was synthesized as a tumor-targeted drug delivery carrier. Cellular uptake of the Au-P (LA-DOX)-b-PEG-OH/FA micelles facilitated by the folate-receptor-mediated endocytosis process was higher than that of the micelles without |
1(0,0,0,1) | Details |
| 20163170 | Yang X, Grailer JJ, Pilla S, Steeber DA, Gong S: Tumor-Targeting, pH-Responsive, and Stable Unimolecular Micelles as Drug Nanocarriers for Targeted Cancer Therapy. Bioconjug Chem. 2010 Feb 17. The -conjugated micelles can be internalized by the cancer cells via folate-receptor-mediated endocytosis; thus, they exhibited enhanced cell uptake and cytotoxicity. The inner hydrophobic layer was composed of random copolymer of poly (epsilon-caprolactone) and poly (PMA-co-PCL) segments, while the outer hydrophilic shell was composed of poly (ethylene glycol) (PEG) segments. |
1(0,0,0,1) | Details |
| 20347138 | Maeng JH, Lee DH, Jung KH, Bae YH, Park IS, Jeong S, Jeon YS, Shim CK, Kim W, Kim J, Lee J, Lee YM, Kim JH, Kim WH, Hong SS: Multifunctional doxorubicin loaded superparamagnetic iron oxide nanoparticles for chemotherapy and magnetic resonance imaging in liver cancer. Biomaterials. 2010 Mar 25. To develop a drug delivery system with enhanced efficacy and minimized adverse effects, we synthesized a novel polymeric nanoparticles, (YCC-DOX) composed of poly (ethylene oxide)-trimellitic anhydride - (PEO-TMA-FA), doxorubicin (DOX) and superparamagnetic iron oxide (Fe (3) O (4)) and YCC-DOX showed the anticancer efficacy and specifically targeted folate receptor (FR)-expressing tumors, thereby increasing the bioavailability and efficacy of DOX. |
1(0,0,0,1) | Details |
| 19712735 | Dosio F, Arpicco S, Stella B, Brusa P, Cattel L: -mediated targeting of albumin conjugates of paclitaxel obtained through a heterogeneous phase system. Int J Pharm. 2009 Dec 1;382(1-2):117-23. Epub 2009 Aug 25. The study developed cytotoxic macromolecular conjugates that specifically target the folate receptor and deliver the drug into cell cytoplasm. The anticancer agent paclitaxel was conjugated to human serum albumin (HSA) and this drug-albumin conjugate was further equipped with linked via an extended poly (ethylene glycol) spacer. |
1(0,0,0,1) | Details |