| 18080289 |
Markussen MD, Heiberg AC, Fredholm M, Kristensen M: Differential expression of cytochrome P450 genes between bromadiolone-resistant and anticoagulant-susceptible Norway rats: a possible role for pharmacokinetics in bromadiolone resistance. Pest Manag Sci. 2008 Mar;64(3):239-48.
This pharmacokinetically based bromadiolone resistance is to some extent sex differentiated, as female resistance furthermore seems to involve overexpression of cytochrome P450-2c13 and suppression of P450-2c12, whereas male resistance appears to involve P450-2a1 overexpression. |
43(0,1,3,3) |
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