| Name | cis 4 |
|---|---|
| Synonyms | CIS 4; SOCS 4; SOCS4; Suppressor of cytokine signaling 4; CIS4; Cish4; Cytokine inducible SH2 protein 4; HSPC060… |
| Name | dieldrin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12770091 | Le Corronc H, Alix P, Hue B: Differential sensitivity of two insect -gated channels to dieldrin, fipronil and picrotoxinin. J Insect Physiol. 2002 Apr;48(4):419-431. With the transient hyperpolarization is sensitive to picrotoxinin, fipronil and dieldrin whereas the slow response is insensitive to these insecticides.When is replaced by muscimol and cis-4-aminocrotonic acid (CACA) a biphasic hyperpolarization consisting of an initial transient hyperpolarization followed by a sustained phase is evoked which is blocked by picrotoxinin and fipronil. |
31(0,1,1,1) | Details |
| 15148245 | Gisselmann G, Plonka J, Pusch H, Hatt H: Drosophila melanogaster GRD and LCCH3 subunits form heteromultimeric -gated cation channels. Br J Pharmacol. 2004 Jun;142(3):409-13. Epub 2004 May 17. The heteromultimeric receptor is activated by (EC50=4.5 microm), muscimol (EC50=4.8 microm) and trans-4-aminocrotonic acid (EC50=104.5 microm), and partially by cis-4-aminocrotonic acid (EC50=106.3 microm). Picrotoxin effectively blocked the -gated channel (IC50=0.25 microm), but bicuculline, TPMTA, dieldrin and lindane did not. |
1(0,0,0,1) | Details |
| 18093001 | Narusuye K, Nakao T, Abe R, Nagatomi Y, Hirase K, Ozoe Y: Molecular cloning of a GABA receptor subunit from Laodelphax striatella (Fallen) and patch clamp analysis of the homo-oligomeric receptors expressed in a Drosophila cell line. Insect Mol Biol. 2007 Dec;16(6):723-33. Antagonists such as fipronil (100 nM), 4'-ethynyl-4-n-propylbicycloorthobenzoate (EBOB) (100 nM), dieldrin (100 nM) and SR95531 (gabazine) (1 microM) suppressed -induced currents. The amplitudes of agonist-induced currents were found to be in the order muscimol (100 microM) >/= (100 microM) > isoguvacine (100 microM) > cis-4-aminocrotonic acid (CACA) (100 microM) > 5-(4-piperidyl)-3-isoxazolol (4-PIOL) (1 mM). |
1(0,0,0,1) | Details |