| 12614680 |
Vale C, Fonfria E, Bujons J, Messeguer A, Rodriguez-Farre E, Sunol C: The organochlorine pesticides gamma-hexachlorocyclohexane (lindane), alpha-endosulfan and dieldrin differentially interact with GABA (A) and glycine-gated chloride channels in primary cultures of cerebellar granule cells. Neuroscience. 2003;117(2):397-403.
Lindane inhibited with similar potency both GABA (A) (IC (50): 6.1 microM) and glycine (5.0 microM) receptors. alpha-Endosulfan and dieldrin inhibited the GABA (A) receptor (IC (50) values: 0.4 microM and 0.2 microM, respectively) more potently than the glycine receptor (IC (50) values: 3.5 microM and 3 microM, respectively). |
87(1,1,1,7) |
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