Protein Information

Name GABA at
Synonyms (S) 3 amino 2 methylpropionate transaminase; 4 aminobutyrate aminotransferase; ABAT; ABAT protein; GABA aminotransferase; GABA transaminase; GABA AT; GABA T…

Compound Information

Name dieldrin
CAS

Reference List

PubMed Abstract RScore(About this table)
7885191 Cole LM, Roush RT, Casida JE: Drosophila GABA-gated chloride channel: modified [3H] EBOB binding site associated with Ala--> Ser or Gly mutants of Rdl subunit. Life Sci. 1995;56(10):757-65.

This specific binding of [3H] EBOB is strongly inhibited by: a large number and variety of insecticidal channel blockers at 20 nM (lindane, alpha-endosulfan, dieldrin, 12-ketoendrin, fipronil, and a representative bicycloorthobenzoate and dithiane) or 200 nM (picrotoxinin); the insecticidal channel activators avermectin and moxidectin at 20 nM; muscimol at 30 microM and GABA at 300 microM.
81(1,1,1,1) Details
10321384 Carr RL, Couch TA, Liu J, Coats JR, Chambers JE: The interaction of chlorinated alicyclic insecticides with brain GABA (A) receptors in channel catfish (Ictalurus punctatus). J Toxicol Environ Health A. 1999 Apr 23;56(8):543-53.

Chlorinated alicyclic insecticides are believed to antagonize the action of the neurotransmitter gamma-aminobutyric acid (GABA) at its receptor in vertebrates.
Dieldrin, lindane, and dihydroaldrin were much less potent (592-1103 nM).
1(0,0,0,1) Details